![]() 苯氧苄胺结构式
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常用名 | 苯氧苄胺 | 英文名 | Phenoxybenzamine HCl |
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CAS号 | 63-92-3 | 分子量 | 340.287 | |
密度 | N/A | 沸点 | 381.5ºC at 760 mmHg | |
分子式 | C18H23Cl2NO | 熔点 | 137.5°C | |
MSDS | 中文版 美版 | 闪点 | 184.5ºC | |
符号 |
![]() ![]() GHS07, GHS08 |
信号词 | Warning |
Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats.
Behav. Brain Res. 281 , 333-8, (2015) The action of PACAP-38 was studied by measuring the anxiogenic-anxiolytic behavior of rats in an elevated plus maze. PACAP-38 was administered into the lateral brain ventricle and the behavior of the animals was measured 3h later. The possible involvement of ... |
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Quantitative high-throughput identification of drugs as modulators of human constitutive androstane receptor.
Sci. Rep. 5 , 10405, (2015) The constitutive androstane receptor (CAR, NR1I3) plays a key role in governing the transcription of numerous hepatic genes that involve xenobiotic metabolism/clearance, energy homeostasis, and cell proliferation. Thus, identification of novel human CAR (hCAR... |
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Targeting the chromosome partitioning protein ParA in tuberculosis drug discovery.
J. Antimicrob. Chemother. 65(11) , 2347-58, (2010) To identify inhibitors of the essential chromosome partitioning protein ParA that are active against Mycobacterium tuberculosis.Antisense expression of the parA orthologue MSMEG_6939 was induced on the Mycobacterium smegmatis background. Screening of syntheti... |
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Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice
Behav. Brain Res. 233(1) , 232-6, (2012) Highlights ► The involvement of transmitters in the anxiolytic action of GH-RH antagonist, MZ-4-71, has been tested in plus maze. ► In the experiments the animals were pretreated with phenoxybenzamine, prazosin, yohimbine, methysergide,cyproheptadine and bicu... |
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Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
Pharmacol. Biochem. Behav. 101(3) , 360-8, (2012) The zona incerta (ZI) is a subthalamic nucleus connected to several structures, some of them known to be involved with antinociception. The ZI itself may be involved with both antinociception and nociception. The antinociceptive effects of stimulating the ZI ... |
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Urocortin 3 administration impairs fear motivated learning in mice is mediated by transmitters.
Behav. Brain Res. 270 , 326-9, (2014) Urocortin 3 (Ucn 3) was found to impair passive avoidance learning in male and female mice. The possible involvement of transmitters in the action, the animals were pretreated with the following receptor antagonists in doses which alone could not influence th... |
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Antidiarrhoeal activity of DAS-77 (a herbal preparation).
Nig. Q. J. Hosp. Med. 21(4) , 317-23, (2011) DAS-77 is a traditional herbal preparation composed of the young callous bark of mango (Mangifera indica Linn., Anacardiaceae) and the dried root of pawpaw (Carica papaya Linn., Caricaceae). This phytomedicine is claimed to have beneficial effects in the trea... |
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Inhibition of nitric oxide-activated guanylyl cyclase by calmodulin antagonists.
Br. J. Pharmacol. 158(6) , 1454-64, (2009) Nitric oxide (NO) controls numerous physiological processes by activation of its receptor, guanylyl cyclase (sGC), leading to the accumulation of 3'-5' cyclic guanosine monophosphate (cGMP). Ca(2+)-calmodulin (CaM) regulates both NO synthesis by NO synthase a... |
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[Preoperative α-receptor block in patients with pheochromocytoma? Against].
Chirurg. 83(6) , 551-4, (2012) Perioperative mortality regarding the resection of catecholamine-producing tumors has been markedly improved. This improvement has been attributed to the preoperative treatment with α-receptor blocking agents. An α-receptor block is still recommended prior to... |
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Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping.
Mol. Pain 6 , 56, (2010) We have previously used the rat 4 day Complete Freund's Adjuvant (CFA) model to screen compounds with potential to reduce osteoarthritic pain. The aim of this study was to identify genes altered in this model of osteoarthritic pain and use this information to... |