二溴乙腈
二溴乙腈结构式
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常用名 | 二溴乙腈 | 英文名 | dibromoacetonitrile |
|---|---|---|---|---|
| CAS号 | 3252-43-5 | 分子量 | 198.84400 | |
| 密度 | 2.29 | 沸点 | 67-69 °C (24 mmHg) | |
| 分子式 | C2HBr2N | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 37°C | |
| 符号 |
GHS06, GHS08, GHS09 |
信号词 | Danger |
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Genotoxic activity of five haloacetonitriles: comparative investigations in the single cell gel electrophoresis (comet) assay and the ames-fluctuation test.
Environ. Mol. Mutagen. 36(1) , 52-8, (2000) Halogenated acetonitriles (HANs) are known to be water disinfectant by-products. Their mutagenicity and carcinogenicity have been shown in different test systems in vivo and in vitro. They also have clastogenic properties. In this study, the ability of HAN to... |
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Neurotoxicological evaluation of two disinfection by-products, bromodichloromethane and dibromoacetonitrile, in rats.
Toxicology 230(2-3) , 137-44, (2007) The Safe Drinking Water Act requires that the U.S. EPA consider noncancer endpoints for the assessment of adverse human health effects of disinfection by-products (DBPs). As an extension of our studies in which we demonstrated neurotoxicity at relatively low ... |
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Dichloroacetonitrile, a by-product of water chlorination, induces aneuploidy in Drosophila.
Mutat. Res. 261(2) , 85-91, (1991) Nitriles have been shown to be potent inducers of aneuploidy in yeast and Drosophila test systems. Haloacetonitriles are by-products of water chlorination that have been shown to be mutagenic and carcinogenic following topical application. In this report we s... |
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Formation of nitrogenous disinfection by-products from pre-chloramination.
Chemosphere 85(7) , 1187-91, (2011) A sampling survey investigated the formation of nitrogenous disinfection by-products (N-DBPs) and carbonaceous DBPs (C-DBPs) from pre-chloramination, an increasingly common treatment strategy in China for regulated C-DBP control, followed by subsequent conven... |
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Toxicology of haloacetonitriles.
Environ. Health Perspect. 69 , 183-202, (1986) Haloacetonitriles are by-products of water chlorination and may form in vivo from the reaction of residual chlorine with endogenous compounds such as amino acids. Dibromoacetonitrile (DBAN) was negative in selected mutagenic assays; dichloroacetonitrile (DCAN... |
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Decomposition of dihaloacetonitriles in water solutions and fortified drinking water samples.
Chemosphere 41(8) , 1149-54, (2000) An investigation of the decomposition of dihaloacetonitriles (DHANs) in water solutions and fortified drinking water samples was conducted. The concentrations of dichloroacetonitrile (CHCl2CN, DCAN), bromochloroacetonitrile (CHBrClCN, BCAN) and dibromoacetoni... |
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Concentrations and correlations of disinfection by-products in municipal drinking water from an exposure assessment perspective.
Environ. Res. 114 , 1-11, (2012) Although disinfection by-products (DBPs) occur in complex mixtures, studies evaluating health risks have been focused in few chemicals. In the framework of an epidemiological study on cancer in 11 Spanish provinces, we describe the concentration of four triha... |
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Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl acrylate, dibromoacetonitrile and 2-hydroxypropionitrile induce chromosome loss in Saccharomyces cerevisiae.
Mutat. Res. 270(2) , 151-66, (1992) Induction of mitotic chromosome loss could be demonstrated for the dialdehyde glyoxal, the diketones 2,3-butanedione and 2,3-hexanedione, ethyl and methyl carbamate, ethyl acrylate, dibromoacetonitrile, 2-hydroxypropionitrile and formaldehyde, but only when t... |
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Potential protective effect of melatonin against dibromoacetonitrile-induced oxidative stress in mouse stomach.
Pharmacol. Res. 46(3) , 287-93, (2002) Dibromoacetonitrile (DBAN) is a disinfection by-product following chlorination of drinking water. Epidemiological studies indicate that it might present a potential hazard to human health. DBAN was previously found to induce oxidative stress in rat stomach as... |
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Percutaneous absorption of haloacetonitriles and chloral hydrate and simulated human exposures.
J. Appl. Toxicol. 32(6) , 387-94, (2012) Disinfection-by-products (DBPs) have long been a human health concern and many are known carcinogens and teratogens. Skin is exposed to DBPs in water through bathing and swimming; however, dermal uptake of many DBPs has not been characterized. The present stu... |