对氟溴苄
对氟溴苄结构式
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常用名 | 对氟溴苄 | 英文名 | 4-Fluorobenzyl bromide |
|---|---|---|---|---|
| CAS号 | 459-46-1 | 分子量 | 189.025 | |
| 密度 | 1.5±0.1 g/cm3 | 沸点 | 195.9±15.0 °C at 760 mmHg | |
| 分子式 | C7H6BrF | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 74.8±15.3 °C | |
| 符号 |
GHS05 |
信号词 | Danger |
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Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors.
Bioorg. Med. Chem. 14(16) , 5742-55, (2006) Because of its essential role in HIV replication and lack of human counterpart, HIV integrase is an attractive target for the development of novel anti-AIDS agents. Among the recently developed integrase inhibitors, only the alpha,gamma-diketo acid (DKA) comp... |
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Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
ChemMedChem 4(8) , 1311-6, (2009) The cellular protein lens epithelium-derived growth factor, or transcriptional coactivator p75 (LEDGF/p75), plays a crucial role in HIV integration. The protein-protein interactions (PPIs) between HIV-1 integrase (IN) and its cellular cofactor LEDGF/p75 may t... |
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Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide.
J. Med. Chem. 51(24) , 8057-67, (2008) Imaging of programmed cell death (apoptosis) is important in the assessment of therapeutic response in oncology and for diagnosis in cardiac and neurodegenerative disorders. The executioner caspases 3 and 7 ultimately effect cellular death, thus providing sel... |