2,3-已二酮
2,3-已二酮结构式
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常用名 | 2,3-已二酮 | 英文名 | hexanedione |
|---|---|---|---|---|
| CAS号 | 3848-24-6 | 分子量 | 114.142 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 125.0±9.0 °C at 760 mmHg | |
| 分子式 | C6H10O2 | 熔点 | -30 °C | |
| MSDS | 中文版 美版 | 闪点 | 32.8±4.4 °C | |
| 符号 |
GHS02, GHS07 |
信号词 | Warning |
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S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity.
Chem. Biol. Interact. 202(1-3) , 136-45, (2013) Carbonyl reductase 1 (CBR1 or SDR21C1) is a ubiquitously-expressed, cytosolic, monomeric, and NADPH-dependent enzyme. CBR1 participates in apoptosis, carcinogenesis and drug resistance, and has a protective role in oxidative stress, cancer and neurodegenerati... |
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Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase – Carbonyl reductase 1
Chem. Biol. Interact. 234 , 162-8, (2015) Curcumin is a major component of the plant Curcuma longa L. It is traditionally used as a spice and coloring in foods and is an important ingredient in curry. Curcuminoids have anti-oxidant and anti-inflammatory properties and gained increasing attention as p... |
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Reduction of lipid peroxidation products and advanced glycation end-product precursors by cyanobacterial aldo-keto reductase AKR3G1—a founding member of the AKR3G subfamily.
FASEB J. 29(1) , 263-73, (2015) The purpose of this study was to investigate the origin and function of the aldo-keto reductase (AKR) superfamily as enzymes involved in the detoxification of xenobiotics. We used the cyanobacterium Synechocystis sp. PCC 6803 as a model organism and sequence ... |
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Inhibition of the reconstituted mitochondrial oxoglutarate carrier by arginine-specific reagents.
Arch. Biochem. Biophys. 331(1) , 48-54, (1996) The effect of arginine-specific reagents on the function of the purified and reconstituted oxoglutarate carrier protein of the inner mitochondrial membrane has been investigated. The alpha-dicarbonyl reagents 2,3-butanedione, 2,3-pentanedione, 2,3- and 3,4-he... |
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Molecular mechanism of hexane neuropathy: significant differences in pharmacokinetics between 2.3-, 2.4-, and 2.5-hexanedione.
Ind. Health 22(3) , 177-87, (1984)
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Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl acrylate, dibromoacetonitrile and 2-hydroxypropionitrile induce chromosome loss in Saccharomyces cerevisiae.
Mutat. Res. 270(2) , 151-66, (1992) Induction of mitotic chromosome loss could be demonstrated for the dialdehyde glyoxal, the diketones 2,3-butanedione and 2,3-hexanedione, ethyl and methyl carbamate, ethyl acrylate, dibromoacetonitrile, 2-hydroxypropionitrile and formaldehyde, but only when t... |
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Male-produced aggregation pheromone of the cerambycid beetle Neoclytus acuminatus acuminatus.
J. Chem. Ecol. 30(8) , 1493-507, (2004) This is the first fully verified report of an aggregation pheromone produced by a cerambycid beetle species. Field bioassays with adult Neoclytus acuminatus acuminatus (F.) (Coleoptera: Cerambycidae) revealed that males produce a pheromone that attracts both ... |
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Apoptotic and necrotic effects of hexanedione derivatives on the human neuroblastoma line SK-N-SH.
Toxicology 231(2-3) , 210-4, (2007) The potential cytotoxicity of two hexanedione food additives (2,3 and 3,4 isomers) was evaluated in comparison with the neurotoxic hexane metabolite 2,5-hexanedione in the human SK-N-SH neuroblastoma line using the MTT assay to indicate mitochondrial dehydrog... |
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A comparison of the apoptotic and cytotoxic effects of hexanedione derivatives on human non-neuronal lines and the neuroblastoma line SH-SY5Y.
Basic Clin Pharmacol Toxicol. 102(1) , 25-9, (2008) The effects of the alpha-diketone derivatives 2,3- and 3,4-hexanediones were investigated in three non-neuronal cell lines (MCF7, HepG(2) and CaCo-2) as well as in the neuroblastoma line, SH-SY5Y. The MTT reduction assay was employed to determine the necrotic... |
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Effect of xanthan on flavor release from thickened viscous food model systems.
J. Agric. Food Chem. 53(9) , 3577-83, (2005) The influence of xanthan concentration (0, 0.02, 0.1, 0.4, and 0.8% w/w) and bulk viscosity on the release of 20 aroma compounds of different chemical classes (5 aldehydes, 4 esters, 5 ketones, 3 alcohols, and 3 terpenes) was evaluated in xanthan-thickened fo... |