1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素
1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素结构式
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常用名 | 1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素 | 英文名 | (Deamino-Pen1,Tyr(Me)2, Arg8)-Vasopressin trifluoroacetate salt |
|---|---|---|---|---|
| CAS号 | 67269-08-3 | 分子量 | 1111.30 | |
| 密度 | 1.49g/cm3 | 沸点 | N/A | |
| 分子式 | C49H70N14O12S2 | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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Arginine vasopressin enhances pHi regulation in the presence of HCO3- by stimulating three acid-base transport systems.
Nature 337(6208) , 648-51, (1989) Growth factors raise intracellular pH (pHi) by stimulating Na+/H+ exchange in the absence of HCO3-. In mutant cells that lack the Na+/H+ exchange activity, this alkalinization does not occur, and the cells do not proliferate without artificial elevation of pH... |
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Arginine vasopressin in advanced vasodilatory shock: a prospective, randomized, controlled study.
Circulation 107(18) , 2313-9, (2003) Vasodilatory shock is a potentially lethal complication of severe disease in critically ill patients. Currently, catecholamines are the most widely used vasopressor agents to support blood pressure, but loss of catecholamine pressor effects is a well-known cl... |
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Role of arginine vasopressin V1 and V2 receptors for brain damage after transient focal cerebral ischemia.
J. Cereb. Blood Flow Metab. 25(8) , 1012-9, (2005) Brain edema formation is one of the most important mechanisms responsible for brain damage after ischemic stroke. Despite considerable efforts, no specific therapy is available yet. Arginine vasopressin (AVP) regulates cerebral water homeostasis and has been ... |
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Androgen-dependent vasopressinergic neurons are involved in social recognition in rats.
Brain Res. 519(1-2) , 150-7, (1990) Socal recognition of juvenile conspecifics by adult male rats has been shown to be modulated by vasopressin. Because part of the extrahypothalamic vasopressinergic innervation of the brain is androgen-dependent, the present experiments were undertaken to asse... |
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Cerebroventricular calcitonin gene-related peptide inhibits rat duodenal bicarbonate secretion by release of norepinephrine and vasopressin.
J. Clin. Invest. 85(1) , 25-32, (1990) Proximal duodenal bicarbonate secretion is an important factor in humans and animals protecting the mucosa against acid-peptic damage. This study examined the mechanisms responsible for the central nervous system regulation of duodenal bicarbonate secretion b... |
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Social recognition does not involve vasopressinergic neurotransmission in female rats.
Brain Res. 535(2) , 301-4, (1990) Social recognition is the ability to recognize a previously investigated conspecific. This phenomenon has been shown to be modulated by androgen-dependent vasopressinergic transmission in intact but not in castrated male rats. The dependence of social recogni... |
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The role of nitric oxide in the development of morphine tolerance in rat hippocampal slices.
Eur. J. Pharmacol. 383(2) , 129-35, (1999) In the present study, we investigated the effects of a nitric oxide (NO) precursor, L-arginine, on the effect of different drugs, [trans-3, 4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamid e hydrochloride] (U-50,488, a kappa-opioid recept... |
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Impaired potentiation by endothelin-1 and vasopressin of sympathetic contraction in tail artery from hypertensive rats.
Cardiovasc. Res. 45(2) , 463-9, (2000) To analyse the effects of endothelin-1 and vasopressin on the sympathetic vasoconstriction during hypertension.Electrical field stimulation (4 Hz) was applied to isolated, 2 mm segments of the tail artery from spontaneously hypertensive (SHR) and normotensive... |
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Androgen-dependent vasopressinergic neurotransmission attenuates interleukin-1-induced sickness behavior.
Brain Res. 557(1-2) , 115-20, (1991) Castrated male rats were found to be more sensitive than intact male rats to the depressing effects of recombinant human interleukin-1 beta (Il-1) on social exploration. This was the case whether Il-1 was injected acutely (1-5 micrograms/rat, i.p.) or continu... |
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Chronic intracerebral infusions of vasopressin and vasopressin antagonist modulate social recognition in rat.
Brain Res. 572(1-2) , 261-4, (1992) To assess the role of androgen-dependent brain vasopressinergic transmission in the modulation of social recognition, castrated male rats which are deficient in vasopressin were implanted intracerebroventricularly with an Accurel collodion mini-device contain... |