1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素

更新时间：2024-01-16 10:01:32

1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素结构式	常用名	1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素	英文名	(Deamino-Pen1,Tyr(Me)2, Arg8)-Vasopressin trifluoroacetate salt
	CAS号	67269-08-3	分子量	1111.30
	密度	1.49g/cm3	沸点	N/A
	分子式	C₄₉H₇₀N₁₄O₁₂S₂	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS07	信号词	Warning

用途

Dp[Tyr(methyl)2,Arg8]-Vasopressin 是一种非选择性肽精氨酸加压素 Vlb 受体拮抗剂。

中文名	1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素
英文名	1-Deaminopenicillamine-2-(O-methyl-tyr)-argipressin
英文别名	更多

描述	Dp[Tyr(methyl)2,Arg8]-Vasopressin 是一种非选择性肽精氨酸加压素 Vlb 受体拮抗剂。
相关类别	信号通路 >> G 蛋白偶联受体/G 蛋白 >> 血管加压素受体研究领域 >> 代谢疾病
参考文献	[1]. Kamal A. Al-Barazanji. Use of vasopressin receptor antagonist for regulation of acth release. WO1997035602A1.

密度	1.49g/cm3
分子式	C₄₉H₇₀N₁₄O₁₂S₂
分子量	1111.30
精确质量	1110.47000
PSA	475.01000
LogP	2.60510
折射率	1.684

符号	GHS07
信号词	Warning
危害声明	H332
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xn
危险品运输编码	NONH for all modes of transport

Arginine vasopressin enhances pHi regulation in the presence of HCO3- by stimulating three acid-base transport systems.

Nature 337(6208) , 648-51, (1989)

Growth factors raise intracellular pH (pHi) by stimulating Na+/H+ exchange in the absence of HCO3-. In mutant cells that lack the Na+/H+ exchange activity, this alkalinization does not occur, and the ...

Arginine vasopressin in advanced vasodilatory shock: a prospective, randomized, controlled study.

Circulation 107(18) , 2313-9, (2003)

Vasodilatory shock is a potentially lethal complication of severe disease in critically ill patients. Currently, catecholamines are the most widely used vasopressor agents to support blood pressure, b...

Role of arginine vasopressin V1 and V2 receptors for brain damage after transient focal cerebral ischemia.

J. Cereb. Blood Flow Metab. 25(8) , 1012-9, (2005)

Brain edema formation is one of the most important mechanisms responsible for brain damage after ischemic stroke. Despite considerable efforts, no specific therapy is available yet. Arginine vasopress...

vasopressin deamino-Pen1,O-Me-tyrosine-2,arginine-8

(DEAMINO-PEN1,TYR(ME)2,ARG8)-VASOPRESSIN

3-mercapto-3-methyl-butyryl-tyr(me)-phe-gln-asn-cys-pro-arg-gly-nh2

[Pmp1,Tyr(OMe)2,Arg8] Vasopressin

1-去氨基青霉胺-2-(O-甲基-酪氨酰)-精氨酸加压素

用途

名称

生物活性

物理化学性质

安全信息

文献30

英文别名