苯亚氨基酸甲酯盐酸盐
苯亚氨基酸甲酯盐酸盐结构式
|
常用名 | 苯亚氨基酸甲酯盐酸盐 | 英文名 | BENZINIDIC ACID METHYL ESTER HYDROCHLORIDE |
|---|---|---|---|---|
| CAS号 | 5873-90-5 | 分子量 | 171.62400 | |
| 密度 | N/A | 沸点 | 171.1ºC at 760mmHg | |
| 分子式 | C8H10ClNO | 熔点 | 105-107ºC (dec.)(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 57.3ºC | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Covalent modification of microsomal lipids by thiobenzamide metabolites in vivo.
Chem. Res. Toxicol. 20(4) , 701-8, (2007) Thiobenzamide (TB) is hepatotoxic in rats causing centrolobular necrosis, steatosis, cholestasis, and hyperbilirubinemia. It serves as a model compound for a number of thiocarbonyl compounds that undergo oxidative bioactivation to chemically reactive metaboli... |
|
|
Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.
J. Biol. Chem. 268(2) , 1066-73, (1993) Members of the snake venon-derived, "disintegrin" peptide family containing the Arg-Gly-Asp (RGD) amino acid sequence are among the most potent inhibitors of the binding of adhesive proteins to platelet glycoprotein (GP) IIb-IIIa. However, GPIIb-IIIa antagoni... |
|
|
Benzamide bioisosteres incorporating dihydroheteroazole substructures: EPC synthesis and SAR leading to a selective dopamine D4 receptor partial agonist (FAUC 179).
Bioorg. Med. Chem. Lett. 11(18) , 2533-6, (2001) Conformationally restricted benzamide bioisosteres were investigated when the chiral phenyldihydroimidazole derivative 4e (FAUC 179) showed strong and highly selective dopamine D4 receptor binding (K(i)high=0.95nM). Mitogenesis experiments indicated partial a... |