1,2,5,6-四氢吡啶
一般危化品
1,2,5,6-四氢吡啶结构式
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常用名 | 1,2,5,6-四氢吡啶 | 英文名 | 1,2,3,6-Tetrahydropyridine |
|---|---|---|---|---|
| CAS号 | 694-05-3 | 分子量 | 83.132 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 110.9±9.0 °C at 760 mmHg | |
| 分子式 | C5H9N | 熔点 | −48 °C(lit.) | |
| MSDS | 美版 | 闪点 | 16.1±0.0 °C | |
| 符号 |
GHS02, GHS07 |
信号词 | Danger |
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The highly-selective 5-HT(1A) agonist F15599 reduces L-DOPA-induced dyskinesia without compromising anti-parkinsonian benefits in the MPTP-lesioned macaque.
Neuropharmacology 97 , 306-11, (2015) L-3,4-dihydroxyphenylalanine (L-DOPA) is the most effective anti-parkinsonian agent available, but upon chronic administration, patients with Parkinson's disease (PD) experience abnormal involuntary movements, dyskinesia. Modulation of serotonin 1A (5-HT1A) r... |
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Neuroprotective effects of 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone in MPTP induced Parkinsonism model in mice.
Neuropharmacology 93 , 209-18, (2015) Parkinson's disease (PD) is a neurological disorder characterized by degeneration of nigrostriatal dopaminergic (DAergic) system. Present treatment targeting to DAergic system solely ameliorated the symptoms but failed to retard the DAergic neuron degeneratio... |
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A new class of ammonium ylid for [2,3]-sigmatropic rearrangement reactions: ene-endo-spiro ylids.
Org. Lett. 7 , 2075, (2005) The first examples of sigmatropic rearrangements of ene-endo-spirocyclic, tetrahydropyridine-derived ammonium ylids are reported. Thus, spiro[6.7]-ylids rearrange primarily by a [2,3]-pathway, whereas the analogous [6.6]-ylids rearrange by [1,2]- and [2,3]-me... |
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Disinhibitory recruitment of NMDA receptor pathways in retina.
J. Neurophysiol. 112(1) , 193-203, (2014) Glutamate release at bipolar to ganglion cell synapses activates NMDA and AMPA/kainic acid (KA) ionotropic glutamate receptors. Their relative strength determines the output signals of the retina. We found that this balance is tightly regulated by presynaptic... |