环氧丙烷
一般危化品
环氧丙烷结构式
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常用名 | 环氧丙烷 | 英文名 | epoxypropane |
|---|---|---|---|---|
| CAS号 | 75-56-9 | 分子量 | 58.079 | |
| 密度 | 0.9±0.1 g/cm3 | 沸点 | 32.9±8.0 °C at 760 mmHg | |
| 分子式 | C3H6O | 熔点 | -112ºC | |
| MSDS | 中文版 美版 | 闪点 | -37.2±0.0 °C | |
| 符号 |
GHS02, GHS06, GHS08 |
信号词 | Danger |
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Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers.
EMBO J. 34(4) , 430-47, (2015) PR-SET7-mediated histone 4 lysine 20 methylation has been implicated in mitotic condensation, DNA damage response and replication licensing. Here, we show that PR-SET7 function in the liver is pivotal for maintaining genome integrity. Hepatocyte-specific dele... |
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SK053 triggers tumor cells apoptosis by oxidative stress-mediated endoplasmic reticulum stress.
Biochem. Pharmacol. 93(4) , 418-27, (2015) Thioredoxins (Trx) together with thioredoxin reductases (TrxR) participate in the maintenance of protein thiol homeostasis and play cytoprotective roles in tumor cells. Therefore, thioredoxin-thioredoxin reductase system is considered to be a promising therap... |
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Transplantation of Human Neural Progenitor Cells Expressing IGF-1 Enhances Retinal Ganglion Cell Survival.
PLoS ONE 10 , e0125695, (2015) We have previously characterized human neuronal progenitor cells (hNP) that can adopt a retinal ganglion cell (RGC)-like morphology within the RGC and nerve fiber layers of the retina. In an effort to determine whether hNPs could be used a candidate cells for... |
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Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration.
PLoS ONE 10 , e0136620, (2015) ERp57 (also known as grp58 and PDIA3) is a protein disulfide isomerase that catalyzes disulfide bonds formation of glycoproteins as part of the calnexin and calreticulin cycle. ERp57 is markedly upregulated in most common neurodegenerative diseases downstream... |
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Autophagy supports survival and phototransduction protein levels in rod photoreceptors.
Cell Death Differ. 22(3) , 488-98, (2015) Damage and loss of the postmitotic photoreceptors is a leading cause of blindness in many diseases of the eye. Although the mechanisms of photoreceptor death have been extensively studied, few studies have addressed mechanisms that help sustain these non-repl... |
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Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease.
Neurobiol. Dis. 73 , 70-82, (2014) Current research on Parkinson's disease (PD) pathogenesis requires relevant animal models that mimic the gradual and progressive development of neuronal dysfunction and degeneration that characterizes the disease. Polymorphisms in engrailed 1 (En1), a homeobo... |
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Consequences of Nosema apis infection for male honey bees and their fertility.
Sci. Rep. 5 , 10565, (2015) The queens of eusocial bees, ants and wasps mate only during a very short period early in life and males therefore produce ejaculates consisting of large numbers of high quality sperm. Such extreme selection for high fecundity resulted in males investing mini... |
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Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis.
MBio 6 , e02428, (2015) Mycobacterium tuberculosis can persist for decades in the human host. Stringent response pathways involving inorganic polyphosphate [poly(P)], which is synthesized and hydrolyzed by polyphosphate kinase (PPK) and exopolyphosphatase (PPX), respectively, are be... |
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Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.
Nat. Commun. 5 , 3793, (2014) Myogenic regulatory factors such as MyoD and Myf5 lie at the core of vertebrate muscle differentiation. However, E-boxes, the cognate binding sites for these transcription factors, are not restricted to the promoters/enhancers of muscle cell-specific genes. T... |
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Disruption of sphingolipid metabolism augments ceramide-induced autophagy in preeclampsia.
Autophagy 11 , 653-69, (2015) Bioactive sphingolipids including ceramides are involved in a variety of pathophysiological processes by regulating cell death and survival. The objective of the current study was to examine ceramide metabolism in preeclampsia, a serious disorder of pregnancy... |