![]() SIB-1893结构式
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常用名 | SIB-1893 | 英文名 | SIB-1893 |
---|---|---|---|---|
CAS号 | 7370-21-0 | 分子量 | 195.26000 | |
密度 | N/A | 沸点 | N/A | |
分子式 | C14H13N | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | N/A | |
符号 |
![]() GHS07 |
信号词 | Warning |
Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP.
Br. J. Pharmacol. 138(6) , 1026-30, (2003) We have identified 2-methyl-6-(2-phenylethenyl)pyridine (SIB-1893) and 2-methyl-6-phenylethynyl pyridine hydrochloride (MPEP) as positive allosteric modulators for the hmGluR4. SIB-1893 and MPEP enhanced the potency and efficacy of L-2-amino-4-phophonobutyrat... |
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SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5.
J. Pharmacol. Exp. Ther. 290 , 170-181, (1999) Cell lines expressing the human metabotropic glutamate receptor subtype 5a (hmGluR5a) and hmGluR1b were used as targets in an automated high-throughput screening (HTS) system that measures changes in intracellular Ca2+ ([Ca2+]i) using fluorescence detection. ... |
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