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SIB-1893

SIB-1893结构式
SIB-1893结构式
品牌特惠专场
常用名 SIB-1893 英文名 SIB-1893
CAS号 7370-21-0 分子量 195.26000
密度 N/A 沸点 N/A
分子式 C14H13N 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP.

Br. J. Pharmacol. 138(6) , 1026-30, (2003)

We have identified 2-methyl-6-(2-phenylethenyl)pyridine (SIB-1893) and 2-methyl-6-phenylethynyl pyridine hydrochloride (MPEP) as positive allosteric modulators for the hmGluR4. SIB-1893 and MPEP enhanced the potency and efficacy of L-2-amino-4-phophonobutyrat...

SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5.

J. Pharmacol. Exp. Ther. 290 , 170-181, (1999)

Cell lines expressing the human metabotropic glutamate receptor subtype 5a (hmGluR5a) and hmGluR1b were used as targets in an automated high-throughput screening (HTS) system that measures changes in intracellular Ca2+ ([Ca2+]i) using fluorescence detection. ...