组胺二盐酸盐
组胺二盐酸盐结构式
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常用名 | 组胺二盐酸盐 | 英文名 | Histamine dihydrochloride |
|---|---|---|---|---|
| CAS号 | 56-92-8 | 分子量 | 184.067 | |
| 密度 | 1.14 g/cm3 | 沸点 | 331ºC at 760 mmHg | |
| 分子式 | C5H11Cl2N3 | 熔点 | 249-252 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 180.3ºC | |
| 符号 |
GHS07, GHS08 |
信号词 | Danger |
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Histamine inhibits differentiation of skin fibroblasts into myofibroblasts.
Biochem. Biophys. Res. Commun. 463 , 434-9, (2015) Histamine and TGF-β, major mediators secreted by mast cells, are involved in skin inflammation and play critical roles in the pathogenesis of systemic sclerosis. However, the roles of signaling mechanisms in the development of skin fibrosis remain largely unc... |
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Involvement of the H1 Histamine Receptor, p38 MAP Kinase, Myosin Light Chains Kinase, and Rho/ROCK in Histamine-Induced Endothelial Barrier Dysfunction.
Microcirculation 22 , 237-48, (2015) The mechanisms by which histamine increases microvascular permeability remain poorly understood. We tested the hypothesis that H1 receptor activation disrupts the endothelial barrier and investigated potential downstream signals.We used confluent EC monolayer... |
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New procedure of selected biogenic amines determination in wine samples by HPLC.
Anal. Chim. Acta 834 , 58-66, (2014) A new procedure for determination of biogenic amines (BA): histamine, phenethylamine, tyramine and tryptamine, based on the derivatization reaction with 2-chloro-1,3-dinitro-5-(trifluoromethyl)-benzene (CNBF), is proposed. The amines derivatives with CNBF wer... |
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An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.
Anal. Sci. 31 , 721-4, (2015) This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a layer of diamine oxidase and a horseradish peroxidase osmium-re... |
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Optimization of soybean processing into kinema, a Bacillus-fermented alkaline food, with respect to a minimum level of antinutrients.
J. Appl. Microbiol. 119 , 162-76, (2015) Optimization of traditional processing of soybeans using response surface methodology (RSM) to achieve a minimum level of antinutritional factors (ANFs) in kinema.Central composite rotatable designs were used to optimize the processing stages of kinema prepar... |
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Storage Time and Temperature Effects on Histamine Production in Tuna Salad Preparations.
J. Food Prot. 78 , 1343-9, (2015) Scombrotoxin fish poisoning (SFP), also known as histamine (Hst) poisoning, has been associated with consumption of scombroid-type fish, including tuna and tuna fish products. Preparation of commercial tuna salad contaminated with Hstproducing bacteria (HPB),... |
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Automated derivatization and fluorimetric determination of biogenic amines in milk by zone fluidics coupled to liquid chromatography.
J. Chromatogr. A. 1356 , 272-6, (2014) A novel zone-fluidics/high pressure liquid chromatographic (ZF-HPLC) method is described for the simultaneous determination of six biogenic monoamines, in the presence of hexylamine as internal standard. Automated on-line derivatization of the analytes with n... |
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Modification and Single-Laboratory Validation of AOAC Official Method 977.13 for Histamine in Seafood to Improve Sample Throughput.
J. AOAC Int. 98 , 622-7, (2015) Histamine is the main causative agent in scombrotoxin fish poisoning, the most frequently reported illness related to fish consumption. The AOAC official method for histamine determination in fish is the fluorometric method AOAC 977.13, which is sensitive and... |
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Binding mechanisms for histamine and agmatine ligands in plasmid deoxyribonucleic acid purifications
J. Chromatogr. A. 1366 , 110-9, (2014) • The versatility of histamine and agmatine ligands in function of binding and elution conditions. • Histamine and agmatine-pDNA multiple interactions depend of salts, ionic strength and pH. • Both ligands showed a biorecognition to the sc pDNA isoform. • The... |
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Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum.
Sensors (Basel.) 15 , 13052-68, (2015) Cameleons are sophisticated genetically encoded fluorescent probes that allow quantifying cellular Ca2+ signals. The probes are based on Förster resonance energy transfer (FRET) between terminally located fluorescent proteins (FPs), which move together upon b... |