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1-氯-2-丙醇

一般危化品
1-氯-2-丙醇结构式
1-氯-2-丙醇结构式
常用名 1-氯-2-丙醇 英文名 1-Chloro-2-propanol
CAS号 127-00-4 分子量 94.540
密度 1.1±0.1 g/cm3 沸点 126.5±0.0 °C at 760 mmHg
分子式 C3H7ClO 熔点 N/A
MSDS 中文版 美版 闪点 54.5±15.3 °C
符号 GHS02 GHS06
GHS02, GHS06
信号词 Danger

NTP Toxicology and Carcinogenesis Studies of 1-Chloro-2-propanol (Technical Grade) (CAS NO. 127-00-4) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies.

Natl. Toxicol. Program Tech. Rep. Ser. 477 , 1-264, (1998)

1-Chloro-2-propanol and its positional isomer, 2-chloro-1-propanol, are used as chemical intermediates for the manufacture of propylene oxide, a starting material for production of polyurethane polyols and propylene glycol. The National Cancer Institute nomin...

Chemical mutagenesis testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program.

Environ. Mol. Mutagen. 23(1) , 51-63, (1994)

Fifty chemicals were tested for mutagenic activity in post-meiotic and meiotic germ cells of male Drosophila melanogaster using the sex-linked recessive lethal (SLRL) assay. As in the previous studies in this series, feeding was chosen as the first route of a...

Haloperoxidases: Enzymatic Synthesis of alpha,beta-Halohydrins from Gaseous Alkenes.

Appl. Environ. Microbiol. 45(2) , 366-74, (1983)

The enzymatic synthesis of alpha,beta-halohydrins from gaseous alkenes is described. The enzymatic reaction required an alkene, a halide ion, dilute hydrogen peroxide, and a haloperoxidase enzyme. A wide range of gaseous alkenes were suitable for this reactio...

Preferential attack of the (S)-configured ether-linked carbons in bis-(1-chloro-2-propyl) ether by Rhodococcus sp. strain DTB.

FEMS Microbiol. Ecol. 55(1) , 113-21, (2006)

Rhodococcus sp. strain DTB (DSM 44534) was grown on a mixture of (R,R)-, (S,S)- and meso-bis-(1-chloro-2-propyl) ether (BCPE) as the sole source of carbon and energy. During BCPE degradation 1'-chloro-2'-propyl-3-chloro-2-prop-1-enyl-ether (DVE), 1-chloro-2-p...

Reproductive toxicology. 1-Chloro-2-propanol.

Environ. Health Perspect. 105 Suppl 1 , 291-2, (1997)

1,2-Dichloropropane: metabolism and fate in the rat.

Xenobiotica 10(11) , 835-46, (1980)

1. The metabolism of 1,2-dichloropropane in the rat has been investigated. The major urinary metabolite has been isolated and identified as N-acetyl-S-(2-hydroxypropyl)cysteine. Two minor metabolites of 1,2-dichloropropane have been identified as beta-chlorol...

Mutagenicity of chloropropanol in a genetic screening battery.

Fundam. Appl. Toxicol. 3(1) , 27-33, (1983)

A 72:25 mixture of 1-chloro-2-propanol and 2-chloro-1-propanol was tested for genetic activity in a battery of short term tests. Chloropropanol was tested over a dose range of 527-167,250 micrograms/plate in the Salmonella/mammalian microsome mutagenicity ass...

Propylene chlorohydrins: toxicology, metabolism, and environmental fate.

Rev. Environ. Contam. Toxicol. 99 , 47-59, (1987)

Disposition of inhaled 1-chloro-2-propanol in F344/N rats.

Toxicol. Appl. Pharmacol. 95(3) , 444-55, (1988)

Propylene chlorohydrins, of which 1-chloro-2-propanol (1-CP) is a constituent, used as intermediates in the manufacture of propylene oxide and have been identified as potential air pollutants. The objective of these studies was to determine whether changes in...

Electrochemical detection of low concentration chloropropanol using silver nanowire array electrodes in aqueous media.

J. Nanosci. Nanotechnol. 11(3) , 2283-6, (2011)

In this paper, we report a facile method to fabricate silver nanowire array electrodes (SNAE) with ultra-high detection sensitivity to chloropropanol in the aqueous solution. Silver nanowire arrays were assembled in conventional anodic alumina membranes (AAM)...