N-乙酰-D-丙氨酸
N-乙酰-D-丙氨酸结构式
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常用名 | N-乙酰-D-丙氨酸 | 英文名 | Ac-D-Ala-OH |
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| CAS号 | 19436-52-3 | 分子量 | 131.130 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 369.7±25.0 °C at 760 mmHg | |
| 分子式 | C5H9NO3 | 熔点 | 128 °C | |
| MSDS | 中文版 美版 | 闪点 | 177.4±23.2 °C |
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Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).
Bioorg. Med. Chem. 16 , 10061-74, (2008) Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of inhibitors as drugs for the treatment of human disease and ... |
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Crystal structures of the complexes between vancomycin and cell-wall precursor analogs.
J. Mol. Biol. 385 , 1422-1432, (2009) The crystal structures of three vancomycin complexes with two vancomycin-sensitive cell-wall precursor analogs (diacetyl-Lys-D-Ala-D-Ala and acetyl-D-Ala-D-Ala) and a vancomycin-resistant cell-wall precursor analog (diacetyl-Lys-D-Ala-D-lactate) were determin... |
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Displacement study on a vancomycin-based stationary phase using N-acetyl-D-alanine as a competing agent.
J. Chromatogr. Sci. 40 , 83-86, (2002) The analysis of the binding data of D,L-dansyl amino acids on a vancomycin stationary phase is investigated in relation to the addition of N-acetyl-D-alanine in the mobile phase. This eluent additive acts as a specific competing agent for the aglycone pocket ... |
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A ligand-mediated dimerization mode for vancomycin.
Chem. Biol. 5 , 293-298, (1998) Vancomycin and related glycopeptide antibiotics exert their antimicrobial effect by binding to carboxy-terminal peptide targets in the bacterial cell wall and preventing the biosynthesis of peptidoglycan. Bacteria can resist the action of these agents by repl... |