卡硝唑
卡硝唑结构式
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常用名 | 卡硝唑 | 英文名 | Carnidazole |
|---|---|---|---|---|
| CAS号 | 42116-76-7 | 分子量 | 244.271 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 422.8±51.0 °C at 760 mmHg | |
| 分子式 | C8H12N4O3S | 熔点 | N/A | |
| MSDS | 中文版 美版 | 闪点 | 209.5±30.4 °C | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Determination of the antitubercular drug PA-824 in rat plasma, lung and brain tissues by liquid chromatography tandem mass spectrometry: application to a pharmacokinetic study.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 988 , 187-94, (2015) A selective, sensitive and high performance liquid chromatography-tandem mass spectrometry (LC-(ESI)MS/MS) method has been developed and validated for the quantification of the potent antitubercular drug candidate, PA-824, in rat plasma, lung and brain tissue... |
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In vitro nitroimidazole resistance of Trichomonas gallinae and successful therapy with an increased dosage of ronidazole in racing pigeons (Columba livia domestica).
J. Vet. Pharmacol. Ther. 15(4) , 409-15, (1992) Six out of eight different Trichomonas gallinae strains isolated from racing pigeons proved to be resistant to the nitroimidazole drugs ronidazole, carnidazole and metronidazole. The minimal cytocidal concentration of ronidazole was determined in in vitro exp... |
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Structural characterization of drugs and oxygenated metabolites by laser microprobe mass spectrometry (LAMMA).
Biomed. Environ. Mass Spectrom. 16(1-12) , 121-9, (1988) Laser microprobe mass analysis (LAMMA) was used for the structural characterization of polyfunctional drugs and their oxygenated metabolites, in particular the N-oxides. The spectra usually yield the molecular weight as well as intense fragments. The structur... |
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[Study of carnidazole (R 25831). A new therapeutic agent for vaginal trichomoniasis].
Rev. Med. Liege. 34(19) , 811-5, (1979)
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Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: structural comparison with form I, the hydrated form and the low energy conformations in vacuo.
J. Pharm. Sci. 95(10) , 2123-36, (2006) The crystal structure of carnidazole form II, O-methyl [2-(2-methyl-5-nitro-1H-imidazole-1-yl)ethyl]thiocarbamate, has been determined using synchrotron X-ray powder diffraction in combination with simulated annealing and whole profile pattern matching, and r... |
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A double-blind controlled clinical trial of carnidazole and tinidazole in the treatment of vaginal trichomoniasis.
Eur. J. Obstet. Gynecol. Reprod. Biol. 10(5) , 325-8, (1980) A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g of carn... |