4-戊炔酸
4-戊炔酸结构式
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常用名 | 4-戊炔酸 | 英文名 | 4-Pentynoic acid |
|---|---|---|---|---|
| CAS号 | 6089-09-4 | 分子量 | 98.100 | |
| 密度 | 1.1±0.1 g/cm3 | 沸点 | 199.2±0.0 °C at 760 mmHg | |
| 分子式 | C5H6O2 | 熔点 | 54-57 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 90.8±17.3 °C | |
| 符号 |
GHS05 |
信号词 | Danger |
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Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic Acid and carnosol derivatives.
Molecules 20 , 8666-86, (2015) Abietane diterpenes exhibit an array of interesting biological activities, which have generated significant interest among the pharmacological community. Starting from the abietane diterpenes carnosic acid and carnosol, twenty four new triazole derivatives we... |
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In situ nanofabrication of hybrid PEG-dendritic-inorganic nanoparticles and preliminary evaluation of their biocompatibility.
Nanoscale 7(9) , 3933-40, (2015) An in situ template fabrication of inorganic nanoparticles using carboxylated PEG-dendritic block copolymers of the GATG family is described as a function of the dendritic block generation, the metal (Au, CdSe) and metal molar ratio. The biocompatibility of t... |
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Surface functionalization of exosomes using click chemistry.
Bioconjug. Chem. 25(10) , 1777-84, (2014) A method for conjugation of ligands to the surface of exosomes was developed using click chemistry. Copper-catalyzed azide alkyne cycloaddition (click chemistry) is ideal for biocojugation of small molecules and macromolecules to the surface of exosomes, due ... |
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Parahydrogen-induced polarization of carboxylic acids: a pilot study of valproic acid and related structures.
NMR Biomed. 27(7) , 810-6, (2014) Parahydrogen-induced polarization (PHIP) is a promising new tool for medical applications of MR, including MRI. The PHIP technique can be used to transfer high non-Boltzmann polarization, derived from parahydrogen, to isotopes with a low natural abundance or ... |
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5-[4-(3,3-Dimethylbutoxycarbonyl)phenyl]-4-pentynoic acid and its derivatives inhibit ionotropic gamma-aminobutyric acid receptors by binding to the 4'-ethynyl-4-n-propylbicycloorthobenzoate site.
Bioorg. Med. Chem. 8(3) , 665-74, (2000) Acyclic noncompetitive antagonists of ionotropic gamma-aminobutyric acid (GABA) receptors, bearing an ester or ether linkage, were designed, synthesized, and assayed for their inhibition of the specific binding of [3H]4'-ethynyl-4-n-propylbicycloorthobenzoate... |
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Preparation of peptide and other biomolecular conjugates through chemoselective ligations.
Methods Mol. Biol. 751 , 67-79, (2011) The synthesis of molecular conjugates through chemoselective ligations represents a very convenient strategy to prepare complex macromolecules with diverse functional elements. Herein, we describe chemical methods based on the preparation of chemoselectively ... |
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Differential efficacy of human mesenchymal stem cells based on source of origin.
J. Org. Chem. 72(26) , 10247-50, (2007) Mesenchymal stem cells (MSCs) are useful in tissue repair but also possess immunomodulatory properties. Murine and uncontrolled human trials suggest efficacy of MSCs in treating lupus. Autologous cells are preferable; however, recent studies suggest that lupu... |
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Tetrahedron Lett. 33 , 2811, (1992)
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Palladium-catalyzed synthesis of new unsaturated exo-enol lactones with potential biological activity. Bouyssi D, et al.
Tetrahedron Lett. 34(19) , 3129-30, (1993)
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Synthesis of molecularly encoded oligomers using a chemoselective "AB + CD" iterative approach.
Macromol. Rapid Commun. 35(2) , 141-5, (2014) A library of eight sequence-defined model oligomers, whose sequence is based on a (0,1) binary code, is prepared through chemoselective repeating cycles of amidification and copper-assisted alkyne-azide cycloaddition reactions from a non-modified Wang resin. ... |