![]() 2,6-二氟苯乙酸结构式
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常用名 | 2,6-二氟苯乙酸 | 英文名 | (2,6-Difluorophenyl)acetic acid |
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CAS号 | 85068-28-6 | 分子量 | 172.129 | |
密度 | 1.4±0.1 g/cm3 | 沸点 | 251.6±25.0 °C at 760 mmHg | |
分子式 | C8H6F2O2 | 熔点 | 100-102 °C(lit.) | |
MSDS | 中文版 美版 | 闪点 | 106.0±23.2 °C | |
符号 |
![]() GHS07 |
信号词 | Warning |
Design and synthesis of Rho kinase inhibitors (II).
Bioorg. Med. Chem. 15 , 350-364, (2007) In a previous study, we identified several structurally unrelated scaffolds of the Rho kinase inhibitor using pharmacophore information obtained from the results of a high-throughput screening and structural information from a homology model of Rho kinase. 1H... |
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Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency.
Bioorg. Med. Chem. Lett. 23(4) , 1110-3, (2013) Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved activity towards Tyr181Cys containing variants was pursued with the assistance of free energy perturbation (FEP) calculations. Optimization of the 4-R substituent in 1 led to eth... |
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