(2,6-Difluorophenyl)acetic acid
(2,6-Difluorophenyl)acetic acid structure
|
Common Name | (2,6-Difluorophenyl)acetic acid | ||
|---|---|---|---|---|
| CAS Number | 85068-28-6 | Molecular Weight | 172.129 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 251.6±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H6F2O2 | Melting Point | 100-102 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 106.0±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Design and synthesis of Rho kinase inhibitors (II).
Bioorg. Med. Chem. 15 , 350-364, (2007) In a previous study, we identified several structurally unrelated scaffolds of the Rho kinase inhibitor using pharmacophore information obtained from the results of a high-throughput screening and structural information from a homology model of Rho kinase. 1H... |
|
|
Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency.
Bioorg. Med. Chem. Lett. 23(4) , 1110-3, (2013) Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved activity towards Tyr181Cys containing variants was pursued with the assistance of free energy perturbation (FEP) calculations. Optimization of the 4-R substituent in 1 led to eth... |
Journals:
More...