高良姜素; 3,5,7-三羟基黄酮
高良姜素; 3,5,7-三羟基黄酮结构式
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常用名 | 高良姜素; 3,5,7-三羟基黄酮 | 英文名 | Galangin |
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| CAS号 | 548-83-4 | 分子量 | 270.237 | |
| 密度 | 1.6±0.1 g/cm3 | 沸点 | 518.6±50.0 °C at 760 mmHg | |
| 分子式 | C15H10O5 | 熔点 | 214-215 °C(lit.) | |
| MSDS | 中文版 美版 | 闪点 | 202.0±23.6 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
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Protective Effect of Plantago major Extract against t-BOOH-Induced Mitochondrial Oxidative Damage and Cytotoxicity.
Molecules 20 , 17747-59, (2015) Plantago major L. produces several chemical substances with anti-inflammatory and analgesic activities and its use in the treatment of oral and throat inflammation in popular medicine is well described. In this study, the antioxidant potential of the Plantago... |
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Ultra high performance liquid chromatography with mass spectrometry method for the simultaneous determination of phenolic constituents in honey from various floral sources using multiwalled carbon nanotubes as extraction sorbents.
J. Sep. Sci. 38 , 2597-606, (2015) An ultra high performance liquid chromatography with mass spectrometry method has been developed for the simultaneous separation, identification and determination of 22 phenolic constituents in honey from various floral sources from Yemen. Solid-phase extract... |
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Combined experimental and in silico approaches for exploring antiperoxidative potential of structurally diverse classes of antioxidants on docetaxel-induced lipid peroxidation using 4-HNE as the model marker.
Bioorg. Chem. 56 , 1-7, (2014) The objective of the present work was tantamount to explain the antiperoxidative potential and structural requirements of twenty-eight structurally diverse classes of antioxidants on docetaxel-induced lipid peroxidation. Both experimental and computational ap... |
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Phytochemical fingerprints of lime honey collected in serbia.
J. AOAC Int. 97(5) , 1259-67, (2015) Composition of phenolic compounds and the sugar content were determined as the basis for characterization of lime honey from Serbia. Particular attention was given to differences in phytochemical profiles of ripe and unripe lime honey and lime tree nectar. Me... |
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Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport.
Drug Metab. Dispos. 42(9) , 1357-66, (2014) Organic anion transporter 1 (OAT1) has been reported to be involved in the nephrotoxicity of many anionic xenobiotics. As current clinically used OAT1 inhibitors are often associated with safety issues, identifying potent OAT1 inhibitors with little toxicity ... |
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Mobilization of Copper ions by Flavonoids in Human Peripheral Lymphocytes Leads to Oxidative DNA Breakage: A Structure Activity Study.
Int. J. Mol. Sci. 16 , 26754-69, (2015) Epidemiological studies have linked dietary consumption of plant polyphenols with lower incidence of various cancers. In particular, flavonoids (present in onion, tomato and other plant sources) induce apoptosis and cytotoxicity in cancer cells. These can the... |
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The flavonols quercetin, myricetin, kaempferol, and galangin inhibit the net oxygen consumption by immune complex-stimulated human and rabbit neutrophils.
Z. Naturforsch., C, J. Biosci. 69(7-8) , 346-56, (2014) Stimulated human neutrophils exhibit increased net oxygen consumption (NOC) due to the conversion of O2 into the superoxide anion by the NADPH oxidase enzymatic complex during the respiratory burst. In several inflammatory diseases, overproduction of these ox... |
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Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model.
Environ. Toxicol. Pharmacol. 36(2) , 288-95, (2013) This study aimed to investigate the effects of galangin on liver fibrosis in rats induced by subcutaneous injection of carbon tetrachloride (CCl4). The administration of CCl4 to rats for 12 weeks caused significant increase of hyaluronic acid, laminin, alanin... |
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3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease.
Pharmacol. Res. 100 , 64-72, (2015) Pregnane X receptor (PXR; NR1I2) is a member of the superfamily of nuclear receptors that regulates the expression of genes involved in various biological processes, including drug transport and biotransformation. In the present study, we investigated the eff... |
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Galangin Prevents Acute Hepatorenal Toxicity in Novel Propacetamol-Induced Acetaminophen-Overdosed Mice.
J. Med. Food 18 , 1187-97, (2015) Acetaminophen (APAP) overdose causes severe liver and kidney damage. APAP-induced liver injury (AILI) represents the most frequent cause of drug-induced liver failure. APAP is relatively insoluble and can only be taken orally; however, its prodrug, propacetam... |