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1,2-二硝基苯

一般危化品
1,2-二硝基苯结构式
1,2-二硝基苯结构式
常用名 1,2-二硝基苯 英文名 1,2-Dinitrobenzene
CAS号 528-29-0 分子量 168.107
密度 1.5±0.1 g/cm3 沸点 319.9±15.0 °C at 760 mmHg
分子式 C6H4N2O4 熔点 116 °C
MSDS 中文版 美版 闪点 169.2±13.2 °C
符号 GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
信号词 Danger

Toxicological aspects of photocatalytic degradation of selected xenobiotics with nano-sized Mn-doped TiO2.

Aquat. Toxicol. 165 , 144-53, (2015)

The toxic effects of two selected xenobiotics, bisphenol A (BPA) and atrazine (ATZ), were evaluated after photocatalytic degradation using nano-sized, Mn-doped TiO2. Undoped and Mn-doped TiO2 nanoparticles were synthesized. The samples were characterized by X...

Functional characterization of glutathione S-transferases associated with insecticide resistance in Tetranychus urticae.

Pestic. Biochem. Physiol. 121 , 53-60, (2015)

The two-spotted spider mite Tetranychus urticae is one of the most important agricultural pests world-wide. It is extremely polyphagous and develops resistance to acaricides. The overexpression of several glutathione S-transferases (GSTs) has been associated ...

Ameliorative action of curcumin in cisplatin-mediated hepatotoxicity: an in vivo study in Wistar rats.

Arch. Med. Res. 45(6) , 462-8, (2014)

Cisplatin (CP) is regarded as a major anticancer drug against a wide spectrum of leukemia and other malignancies. The mode of action of CP on cancer cells is attributed to its property of releasing free radicals which, at the same time, has the potential to d...

Reconstitution of TCR alpha-chain expression in deletion mutants restores dinitrophenyl-specific/class I MHC-restricted suppressor molecule production.

J. Immunol. 154(4) , 1551-9, (1995)

A population of CD8+ T cells from dinitrobenzene sulfonate-primed mice produce soluble effector molecules that down-regulate the magnitude of dinitrophenol-specific contact hypersensitivity reactions. These soluble molecules express the binding specificity an...

Mutagenic reactivities of 3,4-dinitrobiphenyl derivatives.

Mutat. Res. 191(2) , 73-8, (1987)

3,4-Dinitrobiphenyl derivatives were mutagenic in Salmonella typhimurium TA98, TA98/1,8-DNP6 and in TA98NR. We describe here the specific reactivity of 3,4-dinitrobiphenyl derivatives with diluted sodium hydroxide solution and the determination of the amounts...

ROD1, a novel gene conferring multiple resistance phenotypes in Saccharomyces cerevisiae.

J. Biol. Chem. 271(6) , 2914-20, (1996)

Glutathione-dependent detoxification reactions are catalyzed by the enzyme glutathione S-transferase and are important in drug resistance in organisms ranging from bacteria to humans. The yeast Issatchenkia orientalis expresses a glutathione S-transferase (GS...

PY motifs of Rod1 are required for binding to Rsp5 and for drug resistance.

FEBS Lett. 525(1-3) , 131-4, (2002)

In Saccharomyces cerevisiae, the overexpression of ROD1 confers resistance to o-dinitrobenzene (o-DNB), a representative of target drugs of glutathione S-transferase. The roles of Rod1 in drug resistance have remained to be determined. We isolated the rog3 mu...

Comparative vibrational analysis of 1,2-Dinitro benzene and 1-Fluoro-3-nitro benzene: a combined experimental (FT-IR and FT-Raman) and theoretical study (DFT/B3LYP/B3PW91).

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 84(1) , 86-98, (2011)

In this work, the comparative analysis is made on the structure and vibrational spectra of 1,2-Dinitro benzene (1,2-DNB) and 1-Fluoro-3-nitro benzene (1-F-3-NB) molecules. The FT-IR and FT-Raman experimental spectra of the molecules have been recorded using B...

Developmental changes in glutathione S-transferase isoforms expression and activity in intrasplenic fetal liver tissue transplants in rats.

Exp. Toxicol. Pathol. 55(2-3) , 107-19, (2003)

The aim of the present study was to characterise developmental changes in glutathione S-transferase (GST) isoforms expression and in glutathione conjugation capacity in intrasplenic liver tissue transplants. For this purpose, syngenic fetal liver tissue suspe...

Methemoglobin formation in human erythrocytes by nitroaromatic explosives.

Z. Naturforsch., C, J. Biosci. 56(11-12) , 1157-63, (2001)

We have examined the structure-activity relationships in methemoglobin (MetHb) formation by high explosives 2,4,6-trinitrotoluene (TNT), 2,4,6-trinitrophenyl-N-nitramine (tetryl) and 2,4,6-trinitrophenyl-N-nitraminoethylnitrate (pentryl), and a number of mode...