4-氨基-1-萘羧腈
4-氨基-1-萘羧腈结构式
|
常用名 | 4-氨基-1-萘羧腈 | 英文名 | 4-Amino-1-naphthonitrile |
|---|---|---|---|---|
| CAS号 | 58728-64-6 | 分子量 | 168.195 | |
| 密度 | 1.2±0.1 g/cm3 | 沸点 | 392.4±25.0 °C at 760 mmHg | |
| 分子式 | C11H8N2 | 熔点 | 174.5-176.5ºC(lit.) | |
| MSDS | N/A | 闪点 | 191.1±23.2 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
|
Probing the hydrophobic pocket of farnesyltransferase: aromatic substitution of CAAX peptidomimetics leads to highly potent inhibitors.
Bioorg. Med. Chem. 7(12) , 3011-24, (1999) Cysteine farnesylation at the carboxylate terminal tetrapeptide CAAX of Ras protein is catalyzed by farnesyltransferase. This lipid modification is necessary for regulatory function of both normal and oncogenic Ras. The high frequency of Ras mutation in human... |
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