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4-氯-2-甲硫基嘧啶-5-羧酸乙酯

4-氯-2-甲硫基嘧啶-5-羧酸乙酯结构式
4-氯-2-甲硫基嘧啶-5-羧酸乙酯结构式
品牌特惠专场
常用名 4-氯-2-甲硫基嘧啶-5-羧酸乙酯 英文名 Ethyl 4-chloro-2-Methylthio-5-pyriMidinecarboxylate
CAS号 5909-24-0 分子量 232.687
密度 1.4±0.1 g/cm3 沸点 335.7±22.0 °C at 760 mmHg
分子式 C8H9ClN2O2S 熔点 60-63 °C(lit.)
MSDS 中文版 美版 闪点 156.8±22.3 °C
符号 GHS07
GHS07
信号词 Warning

Design and synthesis of a pyrido[2,3-d]pyrimidin-5-one class of anti-inflammatory FMS inhibitors.

Bioorg. Med. Chem. Lett. 18(7) , 2355-61, (2008)

A series of pyrimidinopyridones has been designed, synthesized and shown to be potent and selective inhibitors of the FMS tyrosine kinase. Introduction of an amide substituent at the 6-position of the pyridone core resulted in a significant potency increase. ...