<生产厂家价格>

卡西尼特

卡西尼特用途

Carzenide是有机合成中间体,用于药物合成。

卡西尼特名称

[ CAS 号 ]:
138-41-0

[ 中文名 ]:
对羧基苯磺酰胺

[ 英文名 ]:
Carzenide

[中文别名 ]:

[英文别名 ]:

4-Carboxybenzenesulfonamide
4-Sulfamylbenzoic acid
4-Sulfamoylbenzoic acid
MFCD00007938
carzenide
Benzoic acid, 4-(aminosulfonyl)-
EINECS 205-327-4
p-Sulfamoyl Benzoic Acid

卡西尼特生物活性

[ 描述 ]:

Carzenide是有机合成中间体,用于药物合成。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 其他

[相关活性小分子]

卡西尼特物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
449.0±47.0 °C at 760 mmHg

[ 熔点 ]:
285-295 °C(lit.)

[ 分子式 ]:
C₇H₇NO₄S

[ 分子量 ]:
201.200

[ 闪点 ]:
225.4±29.3 °C

[ 精确质量 ]:
201.009583

[ PSA ]:
105.84000

[ LogP ]:
0.50

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±1.2 mmHg at 25°C

[ 折射率 ]:
1.611

[ 储存条件 ]:
Store at RT.

[ 水溶解性 ]:
453 mg/L (25 ºC)

卡西尼特MSDS

详细MSDS(安全技术说明书)

卡西尼特毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DH6820000

CHEMICAL NAME :: Benzoic acid, p-sulfamoyl-

CAS REGISTRY NUMBER :: 138-41-0

BEILSTEIN REFERENCE NO. :: 1875393

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C7-H7-N-O4-S

MOLECULAR WEIGHT :: 201.21

WISWESSER LINE NOTATION :: ZSWR DVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 38,102,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,548,1965

卡西尼特安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25-S36/37/39-S26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DH6820000

[ 海关编码 ]:
2935009090

卡西尼特合成路线

详细合成路线

卡西尼特上下游产品

卡西尼特上游产品

卡西尼特下游产品

卡西尼特制备

由对甲苯磺酰胺经重铬酸钾氧化而得。另一种氧化操作是使对甲苯磺酰胺与高锰酸钾反应

卡西尼特海关

[ 海关编码 ]: 2935009090

[ 中文概述 ]:
2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:35.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

卡西尼特文献

Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.

Bioorg. Med. Chem. Lett. 21 , 710-4, (2011)

The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catal...

Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.

Bioorg. Med. Chem. 20 , 1403-10, (2012)

The α-carbonic anhydrase (CA, EC 4.2.1.1) Astrosclerin-3 previously isolated from the living fossil sponge Astrosclera willeyana (Jackson et al., Science 2007, 316, 1893), was cloned, kinetically char...

Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.

Bioorg. Med. Chem. 19 , 5023-30, (2011)

The two β-carbonic anhydrases (CAs, EC 4.2.1.1) from the bacterial pathogen Salmonella enterica serovar Typhimurium, stCA 1 and stCA 2, were investigated for their inhibition with a large panel of sul...

更多文献