| 中文名 | 番泻苷元B |
|---|---|
| 英文名 | sennidine b |
| 英文别名 |
(9R,9'S)-4,4',5,5'-Tetrahydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid
1,4-Dichlorobutane-2,3-acetonide meso-4,5-Bis-chlormethyl-2,2-dimethyl-dioxolan Sennidin B [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 9,9',10,10'-tetrahydro-4,4',5,5'-tetrahydroxy-10,10'-dioxo-, (9R,9'S)- |
| 描述 | Sennidin B可从Cassia angustifolia 分离得到,是Sennidin A 的异构体,活性比Sennidin A 低。Sennidin A,能够抑制HCV NS3 解旋酶,其 IC50 值为0.8 μM。Sennidin A诱导Akt和葡萄糖转运蛋白4 (GLUT4) 的磷酸化。Sennidin A刺激葡萄糖掺入。 |
|---|---|
| 相关类别 | |
| 参考文献 |
[2]. Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes. Life Sciences. 2006. |
| 密度 | 1.7±0.1 g/cm3 |
|---|---|
| 沸点 | 801.8±65.0 °C at 760 mmHg |
| 分子式 | C30H18O10 |
| 分子量 | 538.458 |
| 闪点 | 452.6±30.8 °C |
| 精确质量 | 538.090027 |
| PSA | 189.66000 |
| LogP | 8.24 |
| 蒸汽压 | 0.0±3.0 mmHg at 25°C |
| 折射率 | 1.806 |
| 储存条件 | -20°C，密封，干燥 |
|
~%
517-44-2
517-44-2 |
| 文献：Hattori; Kim; Motoike; Kobashi; Namba Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1338 - 1346 |
|
~%
517-44-2
详细
|
| 文献：Hattori; Kim; Motoike; Kobashi; Namba Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1338 - 1346 |
|
~%
517-44-2
517-44-2 |
| 文献：Hattori; Kim; Motoike; Kobashi; Namba Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 4 p. 1338 - 1346 |
| 上游产品 3 | |
|---|---|
| 下游产品 2 | |
