151533-22-1

• 常用中文名：L-5-甲基四氢叶酸钙
• 常用英文名：Levomefolate calcium
• CAS号：151533-22-1
• 分子式：C₂₀H₂₃CaN₇O₆
• 分子量：497.518
• 相关类别： 有机原料 有机金属类化合物 有机钙
• 发布时间：2018-10-02 19:53:45
• 更新时间：2026-07-01 15:33:39
• Levomefolate是叶酸的人造形式,抗叶酸的作用。

名称

• 中文名: L-5-甲基四氢叶酸钙
• 英文名: Levomefolate calcium
• 中文别名: 甲基四氢叶酸钙-叶源酸; 5-甲基四氢叶酸钙 13C5 (消旋); L-5甲基四氢叶酸钙 6S-5甲基四氢叶酸; L-5-甲基四氢叶酸钙(L型); L-5甲基四氢叶酸钙C晶型; 甲基四氢叶酸钙; L-5甲基四氢叶酸钙 6S-5甲基四氢叶酸 活性叶酸; L-五甲基四氢叶酸钙; L-甲基叶酸盐; (S)-2-(4-((((CHEMICALBOOKS)-2-氨基-5-甲基-4-氧代-3,4,5,6,7,8-六氢蝶啶-6-基)甲基)氨基)苯甲酰氨基)戊二酸钙; 左甲基四氢叶酸钙; (6S)-L-5-甲基四氢叶酸钙; 6S-5-甲基四清叶酸钙; L-5-甲基四氢叶酸钙 (L-5-MTHF-Ca); L-5-甲基四氢叶酸钙/L-5-METHYLETRAHYDROFOLATE CALCIUM SALT; (S)-2-(4-((((S)-2-氨基-5-甲基-4-氧代-3,4,5,6,7,8- 六氢蝶啶-6-基)甲基)氨基)苯甲酰氨基)戊二酸钙; 活性叶酸; 6S-5-甲基四氢叶酸钙; 5-L-甲基四氢叶酸钙; 6S-5-甲基四氢叶酸钙(活性叶酸); L-5-甲基四氢叶酸钙-超级叶酸; 左旋甲状腺素钙; 5-甲基四氢叶酸钙
• 英文别名: (6S)-5-methyltetrahydrofolate calcium; Levomefolate (calcium salt); N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl]Methyl]amino]benzoyl]-L-glutaMic Acid CalciuM Salt; Calcium (6S)-5-methyl-tetrahydrofolate; L-5-methyl tetrahydrofolic; l-5-methylfolate; Levomefolinate calcium; (6S)-5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid, calcium salt; 6s-5-methyltetrahydro folatecalclum; Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)be; L-5-Methyletrahydrofolate calcium salt; Bodyfolin; Methyl Folate Calcium Salt (AS); Patented C crystal L-Methylfolate, branded Magnafolate; METHYL FOLATE CALCIUM SALT; L-5-Methyltetrahydrofolate calcium (L-5-MTHF); :4-ISOPROPYL-3-METHYLPHENOL 3-2; N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid calcium salt; L-5-METHYLTETRAHYDROFOLATE CALCIUM 6S; L-5-Methyltetra; METHYL FOLATE CALCIUM SALT(METAFOLIN)(P); L-Glutamic acid, N-[4-[[[(6S)-2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1); L-5-MTHF-Ca; Folic Acid Impurity 3; L-5-Methyltetrahydrofolate calcium; (S)-2-(4-((((S)-2-Amino-5-Methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)amino)benzaMido)pentanedioic acid, calciuM salt; Calcium levomefolate; L-Glutamic acid, N-[4-[[[(6S)-2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1); LMCA; L-5-Methyltetrahydrofolic Acid Calcium; Calcium (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate; calcium laevo-5-methyl tetrahydrofolate; Calcium 5-methyltetrahydrofolate 13C5 (racemic); CALCIUML-5-METHYLTETRAHYDROFOLATEr; Levomefolate calcium //BP; LEVOMEFOLIC CALIUM; L-5 methyl tetrahydrofolat calcium; Levomefolate CalciumQ: What is Levomefolate Calcium Q: What is the CAS Number of Levomefolate Calcium Q: What is the storage condition of Levomefolate Calcium Q: What e the applications of Levomefolate Calcium; 6S-5-methylfolate; Calcium (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate; L-5-MTHF-Ca (L-5-Methyltetrahydrofolate-Ca); Levomefolate Calcium; Levomefolate calcium (LMCA and BAY 0); L-5-Methyltetrahydrofolate Calcium Levome or METHYL FOLATE; L-5-Methyltetrahydrofolate calciuM(L-5-MTHF-Ca); Levo MethylFolate Calcium (LMF); L-5-Methyltetrahydrofolate calcium/Levomefolate calcium; L-5- Methyl leucovorin; Calcium (S)-2-(4-((((S)-2-amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino; (6S)-L-5-methyltetrahydrofolate calcium; Calcium Levomefolate (L-5-Methyltetrahydrofolate Calcium Salt); Dlin; Levomefolate D4 calcium salt; CALCIUML-5-METHYLTETRAHYDROFOLATE; Nutrifolin; CalciuM (S)-2-(4-((((S)-2-amino-5-Methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)Methyl)amino)benzaMido)-4-cboxybutanoate; (6S)-N-[4-(2-Amino-1,4,5,6,7,8,-hexahydro-5-methyl-4-oxo-6-pteridinylmethylamino)benzoyl]-L-glutaminsure, Calciumsalz (1:1); 1-m1-methylcyclopropene; Levomefolate Calcium (Also See: M330135); L-5-Methyletrahydrofolate calciuM

物化性质

• 熔点: >300ºC
• 分子式: C₂₀H₂₃CaN₇O₆
• 分子量: 497.518
• 精确质量: 497.133575
• PSA: 208.43000
• 外观性状: 灰白色至淡黄色固体
• 储存条件: -20?C Freezer

生物活性

• 描述: Levomefolate是叶酸的人造形式,抗叶酸的作用。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 叶酸
  研究领域 >> 癌症
• 参考文献:

  [1]. Fruzzetti F. Beyaz®: an oral contraceptive fortified with folate. Womens Health (Lond Engl). 2012 Jan;8(1):13-9.

  [2]. Wiesinger H, Eydeler U, Richard F, et al. Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone. Clin Drug Investig. 2012 Oct 1;32(10):673-84.

  [3]. Hartmut Blodea, Christine Klippingb, Frank Richardc, et al. Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. Contraception.2012, 85(2), :177-184

  [4]. Rapkin RB, Creinin MD. The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium. Expert Opin Pharmacother. 2011 Oct;12(15):2403-10. doi: 10.1517/14656566.2011.610791.

  [5]. Levomefolic_acid

安全

• 安全声明 (欧洲): 24/25
• 海关编码: 29339900