L-5-甲基四氢叶酸钙

• 常用名: L-5-甲基四氢叶酸钙
• 英文名: Levomefolate calcium
• CAS号: 151533-22-1
• 分子量: 497.518
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₃CaN₇O₆
• 熔点: >300ºC
• 闪点: N/A

L-5-甲基四氢叶酸钙用途

Levomefolate是叶酸的人造形式,抗叶酸的作用。

L-5-甲基四氢叶酸钙名称

• 中文名: L-5-甲基四氢叶酸钙
• 英文名: Levomefolate calcium
• 中文别名: L-甲基叶酸盐

L-5-甲基四氢叶酸钙生物活性

• 描述: Levomefolate是叶酸的人造形式,抗叶酸的作用。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 叶酸
  研究领域 >> 癌症
• 参考文献:

  [1]. Fruzzetti F. Beyaz®: an oral contraceptive fortified with folate. Womens Health (Lond Engl). 2012 Jan;8(1):13-9.

  [2]. Wiesinger H, Eydeler U, Richard F, et al. Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone. Clin Drug Investig. 2012 Oct 1;32(10):673-84.

  [3]. Hartmut Blodea, Christine Klippingb, Frank Richardc, et al. Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. Contraception.2012, 85(2), :177-184

  [4]. Rapkin RB, Creinin MD. The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium. Expert Opin Pharmacother. 2011 Oct;12(15):2403-10. doi: 10.1517/14656566.2011.610791.

  [5]. Levomefolic_acid

L-5-甲基四氢叶酸钙物理化学性质

• 熔点: >300ºC
• 分子式: C₂₀H₂₃CaN₇O₆
• 分子量: 497.518
• 精确质量: 497.133575
• PSA: 208.43000
• InChIKey: VWBBRFHSPXRJQD-QNTKWALQSA-L
• SMILES: CN1c2c([O-])nc(N)nc2NCC1CNc1ccc(C(=O)NC(CCC(=O)[O-])C(=O)O)cc1.[Ca+2]
• 外观性状: 灰白色至淡黄色固体
• 储存条件: -20?C Freezer

L-5-甲基四氢叶酸钙安全信息

• 安全声明 (欧洲): 24/25
• 海关编码: 29339900

L-5-甲基四氢叶酸钙靶点实验

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L-5-甲基四氢叶酸钙英文别名

• Bodyfolin
• CALCIUML-5-METHYLTETRAHYDROFOLATE
• Levomefolinate calcium
• Nutrifolin
• Calcium (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate
• L-5-MTHF-Ca
• L-5-Methyltetrahydrofolate calcium
• Levomefolate Calcium
• L-5-Methyletrahydrofolate calciuM
• Calcium levomefolate
• L-Glutamic acid, N-[4-[[[(6S)-2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1)
• LMCA
• Calcium (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate
• Folic Acid Impurity 3