30197-14-9

• 常用中文名：去氧土大黄苷
• 常用英文名：Desoxyrhaponticin
• CAS号：30197-14-9
• 分子式：C₂₁H₂₄O₈
• 分子量：404.410
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-09-28 13:15:26
• 更新时间：2026-07-03 09:46:34
• Desoxyrhaponticin 是一种来自西藏营养食品 Rheum tanguticum Maxim 的二苯乙烯苷。Desoxyrhaponticin 是一种脂肪酸合成酶 (FAS) 抑制剂,对人类癌细胞具有凋亡作用。

名称

• 中文名: 脱氧土大黄苷
• 英文名: 2-[3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
• 中文别名: (2S,3R,4S,5S,6R)-2-(3-羟基-5-((E)-4-甲氧基苯乙烯基)苯氧基)-6-(羟甲基)四氢-2H-吡喃-3,4,5-三醇; 脱氧根皮苷; 甲基虎杖苷; 甲基虎杖苷标准品; 脱氧土大黄苷 Desoxyrhaponticin; 去氧土大黄苷(脱氧土大黄苷、甲基虎杖苷); 反式-脱氧土大黄苷; 去氧羟基香树脂素; 反式-脱氧土大黄甙; 脱氧土大黄苷,10 MM DMSO 溶液; 去氧土大黄苷 标准品; 土大黄苷, 来源于大黄; 甲基虎杖苷对照品
• 英文别名: Desoxyrhaponticin-RM; deoxyrhapontin from rhubb root; β-D-Glucopyranoside, 3-hydroxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]phenyl; (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol; Resveratrol Impurity 16 (Rhubb); 3-Hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl β-D-glucopyranoside; 3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl β-D-glucopyranoside; Desoxyrhaponticin, 10 mM in DMSO; 3,5-dihydroxy-4'-methoxystilbene 3-o-β-d-glucoside; 3,5-Dihydroxy-4 inverted exclamation marka-methoxystilbene 3-O-|A-D-glucoside; 3-Hydroxy-5-[(E)-2-(4-methoxyphenyl)vinyl]phenyl β-D-glucopyranoside; Deoxyrhapontin; 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE; β-D-Glucopyranoside, 3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl; DEOXYRHAPONTIN(RG); DEOXYRHAPONTIN; trans-Desoxyrhaponticin; (E)-4'-Methoxy-5-(β-D-glucopyranosyloxy)stilbene-3-ol; 3-(β-D-Glucopyranosyloxy)-5-[(E)-2-(4-methoxyphenyl)vinyl]phenol; Deoxyrhaponticin; Deoxyrhapontin from rhubarb root; Deoxyrhapontigenin O-glucoside; Rhaponticin from Rheum officinale Baill

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 700.5±60.0 °C at 760 mmHg
• 分子式: C₂₁H₂₄O₈
• 分子量: 404.410
• 闪点: 377.5±32.9 °C
• 精确质量: 404.147125
• PSA: 128.84000
• LogP: 1.48
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.691
• 储存条件: 2-8°C

生物活性

• 描述: Desoxyrhaponticin 是一种来自西藏营养食品 Rheum tanguticum Maxim 的二苯乙烯苷。Desoxyrhaponticin 是一种脂肪酸合成酶 (FAS) 抑制剂,对人类癌细胞具有凋亡作用。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
  信号通路 >> 代谢酶/蛋白酶 >> 脂肪酸合成酶(FAS)
• 参考文献:

  [1]. Li P, et al. Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells.

安全

• WGK德国: 3

合成路线

197440-96-3 ~% 30197-14-9

文献：Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109

65728-21-4 ~% 30197-14-9

文献：Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109

3462-97-3 ~% 30197-14-9

文献：Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109

187803-40-3 ~% 30197-14-9

文献：Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109

824-94-2 ~% 30197-14-9

文献：Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109

572-09-8 ~% 30197-14-9

文献：Orsini, Fulvia; Pelizzoni, Francesca; Bellini, Barbara; Miglierini, Giuliana Carbohydrate Research, 1997 , vol. 301, # 3-4 p. 95 - 109

94356-29-3 ~% 149-91-7 30197-14-9

文献：Kashiwada, Yoshiki; Nonaka, Gen-ichiro; Nishioka, Itsuo Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 9 p. 3501 - 3517