25999-20-6

• 常用中文名：拉沙洛西钠
• 常用英文名：lasalocid a sodium salt
• CAS号：25999-20-6
• 分子式：C₃₄H₅₃NaO₈
• 分子量：612.77000
• 相关类别： 原料药 抗寄生虫病药 抗原虫药
• 发布时间：2018-09-22 13:15:17
• 更新时间：2026-07-05 18:07:12
• Lasalocid solium是一个抗菌剂。

名称

• 中文名: 拉沙洛西钠
• 英文名: lasalocid a sodium salt
• 中文别名: 拉沙西钠; 拉沙落西钠; 6-((3R,4S,5S,7R)-7-((2S,3S,5S)-5-乙基-5-((2R,5R,6S)-5-乙基-5-羟基-6-甲基四氢-2H-吡喃-2-基)-3-甲基四氢呋喃-2-基)-4-羟基-3,5-二甲基-6-壬酰)-2-羟基-3-甲基苯甲酸钠盐; 拉沙里菌素 (停产); 拉沙洛西钠,10 MM DMSO 溶液; 沙拉洛西钠; 拉沙诺西钠; 拉沙里菌素钠盐; 拉沙洛菌素; 甲醇中拉沙洛西A钠; 甲醇中拉沙洛西钠; 拉沙洛西A钠; 拉沙里菌素; 拉沙里菌素钠溶液; 拉沙洛西钠 A; 拉沙里菌素钠; 甲醇中拉沙里菌素钠溶液标准物质; 拉沙里菌素A 钠盐; 拉沙里菌素 A 钠盐 标准溶液; 拉沙里菌素 A 钠盐 溶液; 拉沙里菌素A钠盐 标准品; 那塞罗钠
• 英文别名: Lasalocid,Inhibitor,inhibit,Lasalocid-A,Lasalocid sodium,Bacterial,Antibiotic,Antibiotic X-537A,Autophagy,Ionophore X-537A; Benzoic acid, 6-[7-[5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-, monosodium salt, [2R-[2.alpha.[2S*(3R*,4S*,5S*,7R*),3S*,5S*],5.alpha.,6.beta.]]; XA14593000ALLasalocid A sodium 100μg/mLin Ace; Lasalocid A sodium salt - 0.1mg/ml, in acetonitrile; AVATEC; LASALOCID, SODIUM SALT; lasalocid sodium salt dimeric form; Lasalocid A sodium salt solution; Lasalocid sodium, 10 mM in DMSO; [2R-2 alpha[2S*(3R*,4S*,5S*,7R*)3S*,5S*,5 alpha,6 beta]]-6-[7-[5-Ethyl-5-(ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid monosodium salt; lasalocidsodium; Lasalocid A Sodium Salt (Solution in acetonitrile 0.1mg/ml); Ionophore X-537A sodium; mt2007; Sodium 6-((3R,4S,5S,7R)-7-((2S,3S,5S)-5-ethyl-5-((2R,5R,6S)-5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)-3-methyltetrahydrofuran-2-yl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methylbenzoate; LasalocidAsodium; Lasalocid A monosodium salt; Lasalocid A sodium 100 μg/mL in Methanol; iasalocid A sodium salt; Nsc243046; Lasalocid A sodium 100 μg/mL in Acetonitrile; Lasalocid sodium A; Antibiotic X-537A sodium; C14593000 Lasalocid A sodium; Lasalocid A sodium in Methanol; BOVATEC; ro2-2985; Lasalocid A Sodium Salt; sodiumlasalocid; Benzoic acid, 6-(3R,4S,5S,7R)-7-(2S,3S,5S)-5-ethyl-5-(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yltetrahydro-3-methyl-2-furanyl-4-hydroxy-3,5-dimethyl-6-oxononyl-2-hydroxy-3-methyl-, monosodium salt; Avatec sodium; Lasalocid sodium ((Lasalocid Sodium) :Avatec); 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-Ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-Methyl-2H-pyran-2-yl]tetrahydro-3-Methyl-2-furanyl]-4-hydroxy-3,5-diMethyl-6-oxononyl]-2-hydroxy-3-Methylbenzoi; 5-dimethyl-6-oxononyl)-yl)tetrahydro-3-methyl-2-furyl)-4-hydroxy-monosodi; lasalocid sodium salt; Lasalocid A SodiuM Salt (Solution in acetonitrile 02.Mg/2Ml); sodiumlasalocida; lasalocid acid sodium salt; Lasalocid (sodium); LASALOCID A NATRIUMSALZ VETRANAL; Lasalocid sodium (Lasalocid-A sodium); Avatec, Bovatec, Ro 5, X 537A; Benzoic acid, 6-[7-[5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl]-4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methyl-, monosodium salt, [2R-[2alpha[2S*(3R*,4S*,5S*,7R*),3S*,5S*],5alpha,6beta; Lasalocid A solution sodium salt; cresoticacid,6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2h-pyran-2; Roche Avatec Type CC; LASALOCID A SODIUM SALT //BP; lasalocidsodiumsalt; Benzoesure, 6-(7-(5-Ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)tetrahydro-3-methyl-2-furanyl)-4-hydroxy-3,5-dimethyl-6-oxononyl)-2-hydroxy-3-methyl-, Mononatriumsalz, (2R-(2alpha(2S*(3R*,4S*,5S*,7R*),3S*,5S*)5alpha,6beta))

物化性质

• 密度: 1.119g/cm3
• 沸点: 735.7ºC at 760mmHg
• 熔点: 180ºC (dec.)(lit.)
• 分子式: C₃₄H₅₃NaO₈
• 分子量: 612.77000
• 闪点: 224.8ºC
• 精确质量: 612.36400
• PSA: 136.35000
• LogP: 4.50750
• 蒸汽压: 1.01E-22mmHg at 25°C
• 折射率: 1.528
• 储存条件: 0-6°C

生物活性

• 描述: Lasalocid solium是一个抗菌剂。
• 相关类别:
  信号通路 >> 自噬 >> 自噬
  信号通路 >> 抗感染 >> 细菌
  天然产物 >> 其他
  研究领域 >> 感染
• 参考文献:

  [1]. Okubo-Kurihara E et al. Modification of plant cell wall structure accompanied by enhancement of saccharification efficiency using a chemical, lasalocid sodium. Sci Rep. 2016 Oct 3;6:34602.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GP4180000 CHEMICAL NAME : Cresotic acid, 6-(7-(5-ethyl-5-(5-ethyltetrahydro-5-hydroxy-6-methyl -2H-pyran-2-yl) tetrahydro-3-methyl-2-furyl)-4-hydroxy-3,5-dimethyl-6 -oxononyl)-, monosodium salt CAS REGISTRY NUMBER : 25999-20-6 LAST UPDATED : 199610 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C34-H53-O8.Na MOLECULAR WEIGHT : 612.86 WISWESSER LINE NOTATION : T6OTJ B1 CQ C2 F- BT5OTJ B2 D1 EY2&VY1&YQY1&2R CQ D1 BVO &-NA- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 146 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978 Volume(issue)/page/year: 3,47,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 64 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978 Volume(issue)/page/year: 3,47,1978

安全

• 危害码 (欧洲): T,Xn,F
• 风险声明 (欧洲): R25
• 安全声明 (欧洲): 28-45-36/37-16
• 危险品运输编码: UN 2811
• RTECS号: GP4180000
• 包装等级: III
• 危险类别: 6.1(b)