73205-13-7

• 常用中文名：氟替卡松丙酸酯USP杂质D
• 常用英文名：Ticabesone Propionate
• CAS号：73205-13-7
• 分子式：C₂₅H₃₂F₂O₅S
• 分子量：482.58000
• 相关类别： 分析化学 标准品 药典标准品和杂志标准品
• 发布时间：2018-09-10 12:21:17
• 更新时间：2026-07-02 07:44:03

名称

• 中文名: 氟替卡松丙酸酯USP杂质D
• 英文名: (6α,8ξ,10ξ,11β,14ξ,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propionat e
• 中文别名: 丙酸氟替卡松杂质D; 氟替卡松相关化合物D; 氟替卡松丙酸酯杂质D; 氟替卡松欧洲药典杂质D; 丙酸氟替卡松 RC D; 氟替卡松杂质4(氟替卡松杂质D); 氟替卡松杂质D; 丙酸氟替卡松杂质06; 丙酸氟替卡松相关化合物D; 丙酸替卡贝松; 丙酸氟替卡松杂质D3; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-二氟-11-羟基-10,13,16-三甲基-17-(甲硫基)羰基)-3-氧代-6,7,8,9,10,11,12,14,15,16,17-十二氢-3H-环戊酸[A]菲-17-基丙酸 (丙酸氟替卡松杂质); 氟替卡松丙酸酯RC D; 丙酸氟替卡松 杂质 D(丙酸氟替卡松 相关化合物 D)
• 英文别名: 6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-17-[(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17alpha-yl Propanoate; Fluticasone Imp D; (6alpha,8xi,10xi,11beta,14xi,16alpha,17alpha)-6,9-difluoro-11-hydroxy-16-methyl-17-[(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17-yl propanoate; Fluticasone Methylsulphanyl Analog; S-methyl p-tolylcarbamothioate; p-Tolyl-thiocarbamidsaeure-S-methylester; Androsta-1,4-diene-17- cbothioic acid,6,9-difluoro-11- hydroxy-16-Methyl-3-oxo-17-(1- oxopropoxy)-, S-Methyl ester, (6α,11β,16α,17α); 6α,9-Difluoro-17-[(methylsulfanyl)carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yle propanoate; Fluticasone Propionate Impurity D/Fluticasone Methylsulphanyl Analog/Ticabesone Propionate/6α,9-Difluoro-17-[(methylsulphanyl)carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-ylpropanoate; Fluticasone Propionate Related Compound D (S-methyl 6alpha, 9alpha-difluoro-11beta-hydroxy-16alpha; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11-hydroxy-10,13,16-trimethyl-17-((methylthio)carbonyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate (Fluticasone Propionate Impurity); 6α,9-difluoro-11β-hydroxy-16α-methyl-17- [(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien-17α-yl propanoate; Fluticasone Impurity D/ Fluticasone Related Compound D (Fluticasone Methylsulphanyl Analog/ Ticabesone Propionate); fluticasone propionate impurity -ZD; 6alpha,9-Difluoro-11beta-hydroxy-16alpha-methyl-17-[(methylsulfanyl)carbonyl]-3-oxoandrosta-1,4-dien; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-17-((methylthio)carbonyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate; Fluticasone Propionate RC D; S-methyl N-(4-methylphenyl)thiocarbamate; Fluticasone Propionate Related Compound D; Fluticasone Impurity 4(Fluticasone Impurity D); Fluticasone Related Compound D; Carbamothioic acid,(4-methylphenyl)-,S-methyl ester; Fluticasone Propionate Impurity D; (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11-hydroxy-10,13,16-trimethyl-17-((methylthio)carbonyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propanoate; p-tolyl-thiocarbamic acid S-methyl ester; S-methyl 4-tolylcarbamothioate; 6α,9-Difluoro-17-[(methylsulphanyl)carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-ylpropanoate; Fluticasone Propionate Related Compound D (F019M0); Fluticasone Propinate impurity D; (6alpha,8xi,10xi,11beta,14xi,16alpha,17alpha)-6,9-difluoro-1; Fluticasone Propionate Impurity D (Fluticasone Propionate Related Compound D)

物化性质

• 密度: 1.29g/cm3
• 沸点: 569.4ºC at 760 mmHg
• 分子式: C₂₅H₃₂F₂O₅S
• 分子量: 482.58000
• 闪点: 298.2ºC
• 精确质量: 482.19400
• PSA: 105.97000
• LogP: 4.13280
• 折射率: 1.563

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

28416-82-2 ~% 73205-13-7

文献：Kertesz, Denis J.; Marx, Michael Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2315 - 2328

2557-49-5 ~% 73205-13-7

文献：Kertesz, Denis J.; Marx, Michael Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2315 - 2328

65429-42-7 ~% 73205-13-7

文献：Kertesz, Denis J.; Marx, Michael Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2315 - 2328

73205-12-6 5188-07-8 ~% 73205-13-7

文献：Kertesz, Denis J.; Marx, Michael Journal of Organic Chemistry, 1986 , vol. 51, # 12 p. 2315 - 2328