溴哌利多

更新时间:2024-01-01 19:44:10

溴哌利多结构式
溴哌利多结构式
品牌特惠专场
常用名 溴哌利多 英文名 Bromperidol
CAS号 10457-90-6 分子量 420.31500
密度 1.366 g/cm3 沸点 543.6ºC at 760 mmHg
分子式 C21H23BrFNO2 熔点 156-158ºC
MSDS N/A 闪点 282.6ºC
符号 GHS07
GHS07
信号词 Warning

 溴哌利多用途


Bromperidol是一种丁酰苯类衍生物,是一种强效且长效的抗精神病药,用于治疗精神分裂症。

 溴哌利多名称

中文名 溴哌利多
英文名 Bromperidol
中文别名 溴哌醇
英文别名 更多

 溴哌利多生物活性

描述 Bromperidol是一种丁酰苯类衍生物,是一种强效且长效的抗精神病药,用于治疗精神分裂症。
相关类别

 溴哌利多物理化学性质

密度 1.366 g/cm3
沸点 543.6ºC at 760 mmHg
熔点 156-158ºC
分子式 C21H23BrFNO2
分子量 420.31500
闪点 282.6ºC
精确质量 419.09000
PSA 40.54000
LogP 4.47260
外观性状 黄褐色固体
蒸汽压 1.19E-12mmHg at 25°C
折射率 1.59
储存条件 库房通风低温干燥,与食品原料类分开存放
水溶解性 H2O: insoluble

 溴哌利多毒性和生态

 溴哌利多安全信息

符号 GHS07
GHS07
信号词 Warning
危害声明 H302
警示性声明 P301 + P312 + P330
危害码 (欧洲) Xn
风险声明 (欧洲) 22
危险品运输编码 NONH for all modes of transport
WGK德国 3
RTECS号 EU1180000
海关编码 2933399090

 溴哌利多合成线路

~58%

溴哌利多结构式

溴哌利多

10457-90-6

文献:Vincent; Shambhu; Digenis Journal of medicinal chemistry, 1980 , vol. 23, # 1 p. 75 - 79

~78%

溴哌利多结构式

溴哌利多

10457-90-6

文献:Moerlein, Stephen M.; Stoecklin, Gerhard L. Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1319 - 1324

 溴哌利多上下游产品

溴哌利多上游产品  1

溴哌利多下游产品  1

 溴哌利多海关

海关编码 2933399090
中文概述 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 溴哌利多文献27

更多文献
Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC–MS/MS: Application on postmortem samples

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 970 , 1-7, (2014)

• The introduction has been modified. • More references have been added to the text. • Limitations of the method have been discussed more in detail.

Sensitive determination of 4-(4-bromophenyl)-4-hydroxypiperidine, a metabolite of bromperidol, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.

Biol. Pharm. Bull. 29(12) , 2479-82, (2006)

The purpose of this study was to determine the level of 4-(4-bromophenyl)-4-hydroxypiperidine (BPHP), a bromperidol (BRO) metabolite, in rat plasma by HPLC with fluorescence detection after pre-column...

Folie à deux: double case-report of shared delusions with a fatal outcome.

Clin. Ter. 162(1) , 45-9, (2011)

Treatment of shared delusional disorder (folie à deux) often involves separation and use of antipsychotic medication, with uncertain outcomes and potential risks.We report on two highly interdependent...

 溴哌利多英文别名

MFCD00866670
4-(4-(4-Bromophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one
EINECS 233-943-3
4-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
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