9,12-Octadecadiynoic Acid

• 常用名: 9,12-Octadecadiynoic Acid
• 英文名: 9,12-Octadecadiynoic acid
• CAS号: 2012-14-8
• 分子量: 276.414
• 密度: 1.0±0.1 g/cm3
• 沸点: 424.0±30.0 °C at 760 mmHg
• 分子式: C₁₈H₂₈O₂
• 熔点: N/A
• 闪点: 202.1±19.2 °C

9,12-Octadecadiynoic Acid用途

Ro 3-1314(9a,12a十八炔二酸)是一种植物脂氧合酶抑制剂。Ro 3-1314是一种亚油酸代谢抑制剂。Ro 3-1314刺激抗原诱导的豚鼠气管螺旋收缩,并从主动致敏豚鼠肺碎片中免疫释放过敏反应慢反应物质(SRS-A)[1]。

9,12-Octadecadiynoic Acid名称

• 中文名: 9,12-十八碳二烯酸
• 英文名: 9,12-Octadecadiynoic acid

9,12-Octadecadiynoic Acid生物活性

• 描述: Ro 3-1314(9a,12a十八炔二酸)是一种植物脂氧合酶抑制剂。Ro 3-1314是一种亚油酸代谢抑制剂。Ro 3-1314刺激抗原诱导的豚鼠气管螺旋收缩,并从主动致敏豚鼠肺碎片中免疫释放过敏反应慢反应物质(SRS-A)[1]。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> 代谢酶/蛋白酶 >> 5脂氧合酶
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. M Hitchcock, et al. Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid. Br J Pharmacol. 1981 Apr;72(4):689-95.

9,12-Octadecadiynoic Acid物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 424.0±30.0 °C at 760 mmHg
• 分子式: C₁₈H₂₈O₂
• 分子量: 276.414
• 闪点: 202.1±19.2 °C
• 精确质量: 276.208923
• PSA: 37.30000
• LogP: 5.75
• InChIKey: KDYILQLPKVZDGB-UHFFFAOYSA-N
• SMILES: CCCCCC#CCC#CCCCCCCCC(=O)O
• 蒸汽压: 0.0±2.2 mmHg at 25°C
• 折射率: 1.490
• 储存条件: -20°C，密闭，干燥

9,12-Octadecadiynoic Acid安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3
• 海关编码: 2916190090

9,12-Octadecadiynoic Acid海关

• 海关编码: 2916190090
• 中文概述: 2916190090 其他不饱和无环一元羧酸（包括其酸酐、酰卤化物，过氧化物和过氧酸以及它们的衍生物）。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙烯酸、丙烯酸盐或酯应报明包装
• 监管条件: A.入境货物通关单 B.出境货物通关单
• 检验检疫: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
• Summary: 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

9,12-Octadecadiynoic Acid靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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9,12-Octadecadiynoic Acid英文别名

• ODYA Ro 3-1314
• octadeca-9,12-diynoic acid
• 9,12-Octadecadiynoic acid