9,12-Octadecadiynoic acid

Modify Date: 2024-01-08 15:36:36

9,12-Octadecadiynoic acid Structure
9,12-Octadecadiynoic acid structure
Common Name 9,12-Octadecadiynoic acid
CAS Number 2012-14-8 Molecular Weight 276.414
Density 1.0±0.1 g/cm3 Boiling Point 424.0±30.0 °C at 760 mmHg
Molecular Formula C18H28O2 Melting Point N/A
MSDS Chinese USA Flash Point 202.1±19.2 °C

 Use of 9,12-Octadecadiynoic acid


Ro 3-1314 (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. Ro 3-1314 is a linoleic acid metabolism inhibitor. Ro 3-1314 stimulates the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substance of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments[1].

 Names

Name 9,12-Octadecadiynoic acid
Synonym More Synonyms

 9,12-Octadecadiynoic acid Biological Activity

Description Ro 3-1314 (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. Ro 3-1314 is a linoleic acid metabolism inhibitor. Ro 3-1314 stimulates the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substance of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments[1].
Related Catalog
References

[1]. M Hitchcock, et al. Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid. Br J Pharmacol. 1981 Apr;72(4):689-95.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 424.0±30.0 °C at 760 mmHg
Molecular Formula C18H28O2
Molecular Weight 276.414
Flash Point 202.1±19.2 °C
Exact Mass 276.208923
PSA 37.30000
LogP 5.75
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.490

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2916190090

 Synthetic Route

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Articles2

More Articles
Bioorthogonal mimetics of palmitoyl-CoA and myristoyl-CoA and their subsequent isolation by click chemistry and characterization by mass spectrometry reveal novel acylated host-proteins modified by HIV-1 infection.

Proteomics 15 , 2066-77, (2015)

Protein acylation plays a critical role in protein localization and function. Acylation is essential for human immunodeficiency virus 1 (HIV-1) assembly and budding of HIV-1 from the plasma membrane i...

Arachidonic acid metabolism and modulation of in vitro anaphylaxis by 5,8,11,14-eicosatetraynoic acid and 9a,12a-octadecadiynoic acid.

Br. J. Pharmacol. 72(4) , 689-95, (1981)

1. 5,8,11,14-Eicosatetraynoic acid (ETYA) inhibited the antigen-induced contractions of tracheal spirals obtained from actively sensitized guinea-pigs. Consistent data were obtained only when the spir...

 Synonyms

ODYA Ro 3-1314
octadeca-9,12-diynoic acid
9,12-Octadecadiynoic acid
Top Suppliers:I want be here


Get all suppliers and price by the below link:

9,12-Octadecadiynoic acid suppliers

9,12-Octadecadiynoic acid price