10-姜酚

• 常用名: 10-姜酚
• 英文名: 10-Gingerol
• CAS号: 23513-15-7
• 分子量: 350.492
• 密度: 1.0±0.1 g/cm3
• 沸点: 499.7±35.0 °C at 760 mmHg
• 分子式: C₂₁H₃₄O₄
• 熔点: 45 - 46 °C
• 闪点: 166.4±19.4 °C

10-姜酚用途

10-Gingerol 是姜根脂的一种主要刺激性成分,具有抗炎、抗氧化和抗增殖活性。10-Gingerol 能抑制 MDA-MB-231 肿瘤细胞的增殖,其 IC50 值为 12.1 μM。

10-姜酚名称

• 中文名: [10]-姜酚
• 英文名: [10]-Gingerol
• 中文别名: 10-姜酮醇 | (S)-5-羟基-1-(4-羟基-3-甲氧基苯基)十四烷-3-酮 | 10-姜辣醇 | 10-姜酚

10-姜酚生物活性

• 描述: 10-Gingerol 是姜根脂的一种主要刺激性成分,具有抗炎、抗氧化和抗增殖活性。10-Gingerol 能抑制 MDA-MB-231 肿瘤细胞的增殖,其 IC50 值为 12.1 μM。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Dugasani S, et al. Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol. J Ethnopharmacol. 2010 Feb 3;127(2):515-20.

  [2]. Almada da Silva J, et al. Purification and differential biological effects of ginger-derived substances on normal and tumor cell lines. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Aug 15;903:157-62.

10-姜酚物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 499.7±35.0 °C at 760 mmHg
• 熔点: 45 - 46 °C
• 分子式: C₂₁H₃₄O₄
• 分子量: 350.492
• 闪点: 166.4±19.4 °C
• 精确质量: 350.245697
• PSA: 66.76000
• LogP: 4.61
• InChIKey: AIULWNKTYPZYAN-SFHVURJKSA-N
• SMILES: CCCCCCCCCC(O)CC(=O)CCc1ccc(O)c(OC)c1
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.513
• 储存条件: 2-8°C
• 水溶解性: methanol: soluble5mg/mL, clear, colorless

10-姜酚MSDS

10-姜酚MSDS英文版

10-姜酚毒性和生态

10-姜酚安全信息

• 危害声明: H413
• 危害码 (欧洲): T+
• 风险声明 (欧洲): 53
• 安全声明 (欧洲): 24/25
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2914509090

10-姜酚海关

• 海关编码: 2914509090
• 中文概述: 2914509090 含其他含氧基的酮. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:5.5% 普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途, 丙酮报明包装
• Summary: HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

10-姜酚靶点实验

查看更多实验

实验名称：Antihelmintic activity against Hymenolepis nana 来源：ChEMBL 靶标：Rodentolepis nana External Id：CHEMBL4006948

实验名称：Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction at 10... 来源：ChEMBL 靶标：Aldo-keto reductase family 1 member B1 External Id：CHEMBL4603181

实验名称：Inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehyde reduction incub... 来源：ChEMBL 靶标：Aldo-keto reductase family 1 member B1 External Id：CHEMBL4603182

实验名称：Aggregation-based inhibition of human recombinant AKR1B1 assessed as D,L-glyceraldehy... 来源：ChEMBL 靶标：Aldo-keto reductase family 1 member B1 External Id：CHEMBL4603184

实验名称：Permeability in human Caco-2 cells assessed as passive diffusion after 3 hrs by HPLC 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL1108199

实验名称：Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as... 来源：ChEMBL 靶标：RBL-2H3 External Id：CHEMBL1052290

实验名称：Antagonist activity at 5HT1A receptor expressed in HEK293 cells assessed as inhibitio... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A External Id：CHEMBL1108198

实验名称：Antagonist activity at 5HT1A receptor expressed in HEK293 cells assessed as inhibitio... 来源：ChEMBL 靶标：5-hydroxytryptamine receptor 1A External Id：CHEMBL1108197

实验名称：Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as... 来源：ChEMBL 靶标：RBL-2H3 External Id：CHEMBL1052288

实验名称：Antiallergic activity in mIgE-DNP and DNP-BSA-stimulated rat RBL2H3 cells assessed as... 来源：ChEMBL 靶标：RBL-2H3 External Id：CHEMBL1052289

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10-姜酚英文别名

• (S)- 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
• (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
• (5s)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)tetradecan-3-one
• <10>-Gingerol
• 10-Gingerol