雏菊叶龙胆酮

• 常用名: 雏菊叶龙胆酮
• 英文名: 3-Methoxy-1,5,8-trihydroxyxanthone
• CAS号: 2798-25-6
• 分子量: 274.226
• 密度: 1.6±0.1 g/cm3
• 沸点: 580.2±50.0 °C at 760 mmHg
• 分子式: C₁₄H₁₀O₆
• 熔点: 265-267ºC
• 闪点: 228.0±23.6 °C

雏菊叶龙胆酮用途

Bellidifolin 是从獐牙菜的茎中提取的一种呫吨酮 (xanthone) 化合物,具有保肝、降血糖、抗氧化、抗炎、抗肿瘤作用。Bellidifolin 能作为病毒蛋白 R (Vpr) 的抑制剂。

雏菊叶龙胆酮名称

• 中文名: 雏菊叶龙胆酮
• 英文名: bellidifolin
• 中文别名: 龙胆山酮酚

雏菊叶龙胆酮生物活性

• 描述: Bellidifolin 是从獐牙菜的茎中提取的一种呫吨酮 (xanthone) 化合物,具有保肝、降血糖、抗氧化、抗炎、抗肿瘤作用。Bellidifolin 能作为病毒蛋白 R (Vpr) 的抑制剂。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 抗感染 >> HIV
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80(22):1187-1192.

  [2]. Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63.

  [3]. Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11.

  [4]. Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7.

雏菊叶龙胆酮物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 580.2±50.0 °C at 760 mmHg
• 熔点: 265-267ºC
• 分子式: C₁₄H₁₀O₆
• 分子量: 274.226
• 闪点: 228.0±23.6 °C
• 精确质量: 274.047729
• PSA: 100.13000
• LogP: 0.90
• InChIKey: JDIORNFCMMYMLF-UHFFFAOYSA-N
• SMILES: COc1cc(O)c2c(=O)c3c(O)ccc(O)c3oc2c1
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.714
• 储存条件: 2-8C

雏菊叶龙胆酮毒性和生态

雏菊叶龙胆酮安全信息

• 海关编码: 2932999099

雏菊叶龙胆酮海关

• 海关编码: 2932999099
• 中文概述: 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

雏菊叶龙胆酮靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：Absorbance-based primary biochemical high throughput screening assay to identify acti... 来源：The Scripps Research Institute Molecular Screening Center 靶标：caspase-3 preproprotein [Homo sapiens] External Id：PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule modulators of NR3A 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：SBCCG-A1015-NR3A-Primary-Assay

实验名称：uHTS identification of small molecule modulators of Rev-erb Alpha. 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：SBCCG-A1016-RevErbaLBD-Primary-Assay

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雏菊叶龙胆酮英文别名

• 1,5,8-trihydroxy-3-methoxyxanthone
• Bellidifolin
• 3-Methoxy-1,5,8-trihydroxyxanthen-9-one
• 1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one
• bellidifodin
• 3-Methoxy-1,5,8-trihydroxyxanthone
• 1,5,8-trihydroxy-3-methoxyxanthen-9-one
• 1,5,8-Trihydroxy-3-methoxy-xanthen-9-on
• 1,5,8-trihydroxy-3-methoxy-xanthen-9-one
• Bellidifolium
• Bellidifoline