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雏菊叶龙胆酮

雏菊叶龙胆酮用途

Bellidifolin 是从獐牙菜的茎中提取的一种呫吨酮 (xanthone) 化合物,具有保肝、降血糖、抗氧化、抗炎、抗肿瘤作用。Bellidifolin 能作为病毒蛋白 R (Vpr) 的抑制剂。

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雏菊叶龙胆酮名称

[ CAS 号 ]:
2798-25-6

[ 中文名 ]:
雏菊叶龙胆酮

[ 英文名 ]:
3-Methoxy-1,5,8-trihydroxyxanthone

[中文别名 ]:

龙胆山酮酚

[英文别名 ]:

1,5,8-trihydroxy-3-methoxyxanthone
9H-Xanthen-9-one, 1,5,8-trihydroxy-3-methoxy-
Bellidifolin
3-Methoxy-1,5,8-trihydroxyxanthen-9-one
1,5,8-Trihydroxy-3-methoxy-9H-xanthen-9-one
bellidifodin
3-Methoxy-1,5,8-trihydroxyxanthone
1,5,8-trihydroxy-3-methoxyxanthen-9-one
1,5,8-Trihydroxy-3-methoxy-xanthen-9-on
1,5,8-trihydroxy-3-methoxy-xanthen-9-one

雏菊叶龙胆酮生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 癌症

信号通路 >> 抗感染 >> HIV

研究领域 >> 感染

研究领域 >> 炎症/免疫

[参考文献]

[1]. Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80(22):1187-1192.

[2]. Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63.

[3]. Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11.

[4]. Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7.

雏菊叶龙胆酮物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
580.2±50.0 °C at 760 mmHg

[ 熔点 ]:
265-267ºC

[ 分子式 ]:
C₁₄H₁₀O₆

[ 分子量 ]:
274.226

[ 闪点 ]:
228.0±23.6 °C

[ 精确质量 ]:
274.047729

[ PSA ]:
100.13000

[ LogP ]:
0.90

[ 蒸汽压 ]:
0.0±1.7 mmHg at 25°C

[ 折射率 ]:
1.714

[ 储存条件 ]:
2-8C

雏菊叶龙胆酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6116500

CHEMICAL NAME :: Xanthen-9-one, 3-methoxy-1,5,8-trihydroxy-

CAS REGISTRY NUMBER :: 2798-25-6

BEILSTEIN REFERENCE NO. :: 0288441

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H10-O6

MOLECULAR WEIGHT :: 274.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 150,141,1985

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雏菊叶龙胆酮安全信息

[ 海关编码 ]:
2932999099

雏菊叶龙胆酮合成路线

详细合成路线

雏菊叶龙胆酮上下游产品

雏菊叶龙胆酮上游产品

雏菊叶龙胆酮下游产品

雏菊叶龙胆酮海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%