甲基泼尼松龙琥珀酸酯

• 常用名: 甲基泼尼松龙琥珀酸酯
• 英文名: Methylprednisolone succinate
• CAS号: 2921-57-5
• 分子量: 474.543
• 密度: 1.3±0.1 g/cm3
• 沸点: 689.6±55.0 °C at 760 mmHg
• 分子式: C₂₆H₃₄O₈
• 熔点: N/A
• 闪点: 230.7±25.0 °C

甲基泼尼松龙琥珀酸酯用途

Methylprednisolone succinate 是一种合成的糖皮质激素,被广泛用作抗炎剂。

甲基泼尼松龙琥珀酸酯名称

• 中文名: 甲基泼尼松龙琥珀酸酯
• 英文名: 4-[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid
• 中文别名: 甲基泼尼松龙琥珀酸 | 琥珀酸甲泼尼龙 | 琥珀酸甲泼尼龙

甲基泼尼松龙琥珀酸酯生物活性

• 描述: Methylprednisolone succinate 是一种合成的糖皮质激素,被广泛用作抗炎剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 糖皮质激素受体
  研究领域 >> 癌症
  研究领域 >> 炎症/免疫
• 靶点实验:

  glucocorticoid receptor[1]

• 参考文献:

  [1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6.

  [2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000.

甲基泼尼松龙琥珀酸酯物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 689.6±55.0 °C at 760 mmHg
• 分子式: C₂₆H₃₄O₈
• 分子量: 474.543
• 闪点: 230.7±25.0 °C
• 精确质量: 474.225372
• PSA: 138.20000
• LogP: 2.69
• InChIKey: IMBXEJJVJRTNOW-XYMSELFBSA-N
• SMILES: CC1CC2C(C(O)CC3(C)C2CCC3(O)C(=O)COC(=O)CCC(=O)O)C2(C)C=CC(=O)C=C12
• 蒸汽压: 0.0±4.9 mmHg at 25°C
• 折射率: 1.593
• 储存条件: 2-8℃

甲基泼尼松龙琥珀酸酯安全信息

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2942000000

甲基泼尼松龙琥珀酸酯海关

• 海关编码: 2942000000

甲基泼尼松龙琥珀酸酯靶点实验

查看更多实验

实验名称：Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellula... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291801

实验名称：Agonist activity at human GABRA1 in an in vitro cell-based assay measured by fluoresc... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit gamma-2 External Id：CHEMBL5291796

实验名称：Binding affinity towards rat Gabra1 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit alpha-1 External Id：CHEMBL5291798

实验名称：Antagonist activity at human GABRA1 in an in vitro cell-based assay measured by fluor... 来源：ChEMBL 靶标：Gamma-aminobutyric acid receptor subunit gamma-2 External Id：CHEMBL5291797

实验名称：Binding affinity towards human ESR1 in an in vitro cell free assay (NIBR assay) measu... 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL5291791

实验名称：Binding affinity towards human HRH3 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：Histamine H3 receptor External Id：CHEMBL5291921

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Binding affinity towards human EDNRA in an in vitro assay with cellular components me... 来源：ChEMBL 靶标：Endothelin-1 receptor External Id：CHEMBL5291785

实验名称：Binding affinity towards human DRD2 in an in vitro assay with cellular components mea... 来源：ChEMBL 靶标：D(2) dopamine receptor External Id：CHEMBL5291781

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甲基泼尼松龙琥珀酸酯英文别名

• Urbason-Soluble
• methylprednisolone 21-hemisuccinate
• Butanedioic acid, mono[(6α,11β)-11,17-dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester
• MFCD00271782
• 4-{[(6α,11β)-11,17-Dihydroxy-6-methyl-3,20-dioxopregna-1,4-dien-21-yl]oxy}-4-oxobutanoic acid
• Methylprednisolone sodium hemisuccinate
• 6-methylprednisolone-21-hemisuccinate
• methylprednisolone hemisuccinate esters
• Methylprednisolone hydrogen succinate
• Solumedrol
• EINECS 220-863-9
• UNII-5GMR90S4KN
• METHYLPREDNISOLONE SODIUM SUCCINATE
• 11b,17,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione 21-(Hydrogen Succinate)
• Methylprednisolone hemisuccinate
• methylprednisolone succinate