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甲基泼尼松龙琥珀酸酯

甲基泼尼松龙琥珀酸酯用途

Methylprednisolone succinate 是一种合成的糖皮质激素,被广泛用作抗炎剂。

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甲基泼尼松龙琥珀酸酯名称

[ CAS 号 ]:
2921-57-5

[ 中文名 ]:
甲基泼尼松龙琥珀酸酯

[ 英文名 ]:
Methylprednisolone succinate

[中文别名 ]:

[英文别名 ]:

Urbason-Soluble
methylprednisolone 21-hemisuccinate
MFCD00271782
Methylprednisolone sodium hemisuccinate
6-methylprednisolone-21-hemisuccinate
methylprednisolone hemisuccinate esters
Methylprednisolone hydrogen succinate
Solumedrol
EINECS 220-863-9
UNII-5GMR90S4KN

甲基泼尼松龙琥珀酸酯生物活性

[ 描述 ]:

Methylprednisolone succinate 是一种合成的糖皮质激素,被广泛用作抗炎剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 糖皮质激素受体

研究领域 >> 癌症

研究领域 >> 炎症/免疫

[ 靶点 ]

glucocorticoid receptor[1]

[参考文献]

[1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6.

[2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000.

[相关活性小分子]

甲基泼尼松龙琥珀酸酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
689.6±55.0 °C at 760 mmHg

[ 分子式 ]:
C₂₆H₃₄O₈

[ 分子量 ]:
474.543

[ 闪点 ]:
230.7±25.0 °C

[ 精确质量 ]:
474.225372

[ PSA ]:
138.20000

[ LogP ]:
2.69

[ 蒸汽压 ]:
0.0±4.9 mmHg at 25°C

[ 折射率 ]:
1.593

[ 储存条件 ]:
2-8℃

甲基泼尼松龙琥珀酸酯安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2942000000

甲基泼尼松龙琥珀酸酯合成路线

详细合成路线

甲基泼尼松龙琥珀酸酯海关

[ 海关编码 ]: 2942000000

甲基泼尼松龙琥珀酸酯文献

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Shoe contact dermatitis is common in both the pediatric and the adult populations. Severity of the reaction can vary greatly by patient.Health Care Professionals of all types should be familiar with s...

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