Fipexide hydrochloride

• 常用名: Fipexide hydrochloride
• 英文名: Attentil
• CAS号: 34161-23-4
• 分子量: 425.30600
• 密度: 1.342g/cm3
• 沸点: 559.3ºC at 760 mmHg
• 分子式: C₂₀H₂₂Cl₂N₂O₄
• 熔点: N/A
• 闪点: 292.1ºC

Fipexide hydrochloride用途

Fipexide hydrochloride 是对氯苯乙酸衍生物,是一种促智药物。Fipexide hydrochloride 降低了纹状体腺苷酸环化酶 (adenylate cyclase) 的活性。Fipexide hydrochloride 通过多巴胺能神经传递对认知表现出积极的作用。Fipexide hydrochloride 具有用于老年痴呆研究的潜力。

Fipexide hydrochloride名称

• 中文名: 非哌西特盐酸盐
• 英文名: fipexide hydrochloride

Fipexide hydrochloride生物活性

• 描述: Fipexide hydrochloride 是对氯苯乙酸衍生物,是一种促智药物。Fipexide hydrochloride 降低了纹状体腺苷酸环化酶 (adenylate cyclase) 的活性。Fipexide hydrochloride 通过多巴胺能神经传递对认知表现出积极的作用。Fipexide hydrochloride 具有用于老年痴呆研究的潜力。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 腺苷酸环化酶
  信号通路 >> 神经信号通路 >> 多巴胺转运蛋白
  研究领域 >> 神经疾病
• 参考文献:

  [1]. A Marino, et al. Fipexide improvement of cognitive functions in rat: behavioural and neurochemical studies. Pharmacol Res. Mar-Apr 1990;22(2):179-87.

Fipexide hydrochloride物理化学性质

• 密度: 1.342g/cm3
• 沸点: 559.3ºC at 760 mmHg
• 分子式: C₂₀H₂₂Cl₂N₂O₄
• 分子量: 425.30600
• 闪点: 292.1ºC
• 精确质量: 424.09600
• PSA: 51.24000
• LogP: 3.46970
• InChIKey: MVOWQBJZZKOQNU-UHFFFAOYSA-N
• SMILES: Cl.O=C(COc1ccc(Cl)cc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
• 储存条件: -20°C

Fipexide hydrochloride毒性和生态

Fipexide hydrochloride安全信息

• 危害码 (欧洲): Xn

Fipexide hydrochloride靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree... 来源：824 靶标：N/A External Id：P53600

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce... 来源：824 靶标：N/A External Id：P53MS958

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary 来源：824 External Id：P53MS482

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Fipexide hydrochloride英文别名

• 1-[2-(4-CHLOROPHENOXY)ACETYL]-4-[3,4-METHYLENEDIOXYBENZYL]PIPERAZINE HYDROCHLORIDE
• 1-(3',4'-methylenedioxybenzyl)-4-(4-chlorophenoxyacetyl)-piperazine hydrochloride
• 1-(1,3-benzodioxol-5-ylmethyl)-4-[(4-chlorophenoxy)acetyl]piperazinium chloride
• Vigilor
• 1-(1,3-Benzodioxol-5-yl-methyl)-4-[(4-chlorophenoxy)acetyl]piperazine hydrochloride
• Attentil
• 1-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-2-(4-chlorophenoxy)ethanone hydrochloride
• BP-662