11β-Prostaglandin E2

• 常用名: 11β-Prostaglandin E2
• 英文名: 11β-Prostaglandin E2
• CAS号: 38310-90-6
• 分子量: 352.465
• 密度: 1.1±0.1 g/cm3
• 沸点: 530.1±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₂O₅
• 熔点: N/A
• 闪点: 288.5±26.6 °C

11β-Prostaglandin E2用途

11β-前列腺素E2(11β-地诺前列酮)是一种前列腺素衍生物,在Ki为53.3 nM的大鼠中抑制[3H]PGE2与下丘脑膜的结合[1]。

11β-Prostaglandin E2名称

• 英文名: 7-[(1R,2R,3S)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid

11β-Prostaglandin E2生物活性

• 描述: 11β-前列腺素E2(11β-地诺前列酮)是一种前列腺素衍生物,在Ki为53.3 nM的大鼠中抑制[3H]PGE2与下丘脑膜的结合[1]。
• 相关类别:
  研究领域 >> 内分泌
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 前列腺素受体
• 参考文献:

  [1]. F Dray, M Heaulme, et al. Prostaglandins of the E series inhibit release of noradrenaline in rat hypothalamus by a mechanism unrelated to classical alpha 2 adrenergic presynaptic inhibition. Neuropharmacology. 1984 Apr;23(4):457-62.

11β-Prostaglandin E2物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 530.1±50.0 °C at 760 mmHg
• 分子式: C₂₀H₃₂O₅
• 分子量: 352.465
• 闪点: 288.5±26.6 °C
• 精确质量: 352.224976
• PSA: 94.83000
• LogP: 1.88
• 蒸汽压: 0.0±3.2 mmHg at 25°C
• 折射率: 1.561

11β-Prostaglandin E2英文别名

• l-7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
• (5Z,11β,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
• (5E,13E)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
• 5-Heptenoic acid, 7-[3-hydroxy-2- (3-hydroxy-1-octenyl)-5-oxocyclopentyl]-
• 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-
• 7-(3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-5-heptenoic acid
• (5E)-7-{3-Hydroxy-2-[(1E)-3-hydroxy-1-octen-1-yl]-5-oxocyclopentyl}-5-heptenoic acid
• Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11β,13E,15S)-
• prostaglandin-E2
• 5-Heptenoic acid, 7-(3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl)-, l-
• Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5E,13E)-
• 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid