头孢洛宁

• 常用名: 头孢洛宁
• 英文名: Cephalonium
• CAS号: 5575-21-3
• 分子量: 458.51
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₈N₄O₅S₂
• 熔点: 147-150° (dec)
• 闪点: N/A

头孢洛宁用途

头孢洛尼是第一代β-内酰胺头孢菌素类抗生素,广泛用于研究包括葡萄球菌在内的革兰氏阳性菌引起的乳腺炎[1][2][3]。

头孢洛宁名称

• 中文名: 头孢洛宁 水合物
• 英文名: (6R,7R)-3-[(4-carbamoylpyridin-1-ium-1-yl)methyl]-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 中文别名: 头孢洛宁

头孢洛宁生物活性

• 描述: 头孢洛尼是第一代β-内酰胺头孢菌素类抗生素,广泛用于研究包括葡萄球菌在内的革兰氏阳性菌引起的乳腺炎[1][2][3]。
• 相关类别:
  研究领域 >> 感染
  研究领域 >> 炎症/免疫
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  β-lactam

• 参考文献:

  [1]. Harada K, et, al. Assessment of the Usefulness of Cefapirin and Cefalonium Disks for Susceptibility Testing of Staphylococcus aureus Isolates from Bovine Mastitis. Antibiotics (Basel). 2020 Apr 21;9(4):197.

  [2]. Demon D, et, al. The intramammary efficacy of first generation cephalosporins against Staphylococcus aureus mastitis in mice. Vet Microbiol. 2012 Nov 9;160(1-2):141-50.

  [3]. Berry EA, et, al. Effect of an intramammary teat seal and dry cow antibiotic in relation to dry period length on postpartum mastitis. J Dairy Sci. 2007 Feb;90(2):760-5.

头孢洛宁物理化学性质

• 熔点: 147-150° (dec)
• 分子式: C₂₀H₁₈N₄O₅S₂
• 分子量: 458.51
• 精确质量: 458.07200
• PSA: 190.05000
• InChIKey: FMZXNVLFJHCSAF-DNVCBOLYSA-N
• SMILES: NC(=O)c1cc[n+](CC2=C(C(=O)[O-])N3C(=O)C(NC(=O)Cc4cccs4)C3SC2)cc1
• 储存条件: 2-8°C

头孢洛宁毒性和生态

头孢洛宁安全信息

• 危害码 (欧洲): Xn

头孢洛宁靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree... 来源：824 靶标：N/A External Id：P53600

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce... 来源：824 靶标：N/A External Id：P53MS958

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary 来源：824 External Id：P53MS482

实验名称：p53 small molecule agonists, cell-based qHTS assay 来源：824 External Id：P53344

实验名称：p53 small molecule agonists, cell-based qHTS assay with human liver microsomes 来源：824 靶标：tumor suppressor p53 [Homo sapiens] External Id：P53MS233

实验名称：p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ... 来源：824 靶标：N/A External Id：P53MS837

实验名称：p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes 来源：824 靶标：tumor suppressor p53 [Homo sapiens] External Id：P53MS898

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

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头孢洛宁英文别名

• Cephalonium
• Cefalonum
• Cefalonio [INN-Spanish]
• Cefalonium [INN-Latin]
• Cefalonium Hydrate
• CEFALONIUM
• EINECS 226-948-7