Meticillin

更新时间：2024-01-15 20:04:58

Meticillin结构式	常用名	Meticillin	英文名	Meticillin
	CAS号	61-32-5	分子量	380.41600
	密度	N/A	沸点	N/A
	分子式	C₁₇H₂₀N₂O₆S	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS07	信号词	Warning

Meticillin用途

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甲氧西林是一种窄谱β-内酰胺抗生素,通过抑制青霉素结合蛋白(PBPs)发挥作用。甲氧西林对其他青霉素耐药的金黄色葡萄球菌和表皮葡萄球菌具有活性。甲氧西林可用于研究皮肤感染、骨髓炎和心内膜炎[1]。

英文名	methicillin
英文别名	更多

描述	甲氧西林是一种窄谱β-内酰胺抗生素,通过抑制青霉素结合蛋白(PBPs)发挥作用。甲氧西林对其他青霉素耐药的金黄色葡萄球菌和表皮葡萄球菌具有活性。甲氧西林可用于研究皮肤感染、骨髓炎和心内膜炎[1]。
相关类别	研究领域 >> 感染信号通路 >> 抗感染 >> 细菌
体外研究	甲氧西林(20μg/mL,24小时)导致金黄色葡萄球菌的CFU快速下降[2]。
体内研究	金黄色葡萄球菌中的甲氧西林(肌肉注射,每6小时,5天40毫克/公斤)-受感染的兔子[2]。
参考文献	[1]. Sharon S. Castle. Methicillin. xPharm: The Comprehensive Pharmacology Reference 2007, Pages 1-4. [2]. Jaime Carrizosa, et al. Treatment of Experimental Staphylococcus aureus Endocarditis: Comparison of Cephalothin, Cefazolin, and Methicillin. Antimicrob Agents Chemother. 1978 Jan; 13(1): 74–77.

分子式	C₁₇H₂₀N₂O₆S
分子量	380.41600
精确质量	380.10400
PSA	130.47000
LogP	1.27790

符号	GHS07
信号词	Warning
危害声明	H302
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危险品运输编码	NONH for all modes of transport
RTECS号	XH8930000

Meticillin上游产品 0
Meticillin下游产品 1
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