洛贝林

• 常用名: 洛贝林
• 英文名: (-)-Lobeline
• CAS号: 90-69-7
• 分子量: 337.455
• 密度: 1.1±0.1 g/cm3
• 沸点: 485.6±15.0 °C at 760 mmHg
• 分子式: C₂₂H₂₇NO₂
• 熔点: 130-131°
• 闪点: 247.5±20.4 °C

洛贝林用途

Lobeline (α-Lobeline; L-Lobeline), a lipophilic alkaloidal, is a nicotinic receptor agonist. Lobeline inhibits d-methamphetamine self-administration with no dopaminergic toxicity. Lobeline rescues d-amphetamine abuse induced addictive effect. Lobeline increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage[1][2][3].

洛贝林名称

• 中文名: 洛贝林
• 英文名: (-)-lobeline

洛贝林物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 485.6±15.0 °C at 760 mmHg
• 熔点: 130-131°
• 分子式: C₂₂H₂₇NO₂
• 分子量: 337.455
• 闪点: 247.5±20.4 °C
• 精确质量: 337.204193
• PSA: 40.54000
• LogP: 3.61
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.563
• 储存条件: 库房低温通风干燥,与食品原料分开存放

洛贝林安全信息

• 危害码 (欧洲): T
• 风险声明 (欧洲): 23/24/25
• 安全声明 (欧洲): 36/37/39-45
• 危险品运输编码: UN 1544
• 包装等级: III
• 危险类别: 6.1(b)

洛贝林英文别名

• [2R-[2a,6a(S*)]]-2-[6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenylethanone
• 2-{(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
• 2-{(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl}-1-phenylethanone
• Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-
• lobeline
• Lobron
• Bantron
• Inflatine
• 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone
• Zoolobelin
• Lobelina