4-Nitrobenzonitrile
4-Nitrobenzonitrile structure
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Common Name | 4-Nitrobenzonitrile | ||
|---|---|---|---|---|
| CAS Number | 619-72-7 | Molecular Weight | 148.119 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 307.7±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H4N2O2 | Melting Point | 144-147 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 139.9±23.2 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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[A case of methemoglobinemia due to 4-nitrobenzonitrile exposure].
Med. Lav. 82(2) , 137-41, (1991) The paper describes a singular case of acute intoxication by 4-nitrobenzonitrile, a rare intermediate compound produced by pharmaceutical synthesis. The patients subsequently showed an increase in triglycerides and fatty alterations of the liver. |
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Release of nitrite from the antitubercular nitroimidazole drug PA-824 and analogues upon one-electron reduction in protic, non-aqueous solvent.
Org. Biomol. Chem. 8(2) , 413-8, (2010) The one-electron reduction chemistry of the antituberculosis drug PA-824, together with a series of closely related compounds, has been investigated in irradiated anaerobic propan-2-ol solution. The protic solvent, of low dielectric constant, was chosen to mi... |
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In vitro metabolism of aromatic nitriles.
J. Pharm. Sci. 83(12) , 1729-34, (1994) Studies on the metabolic fate of aromatic nitriles, in contrast to their aliphatic counterparts, have been minimal and the subject of controversy. The in vitro metabolic fate of several aromatic nitriles with varying substituents was investigated by using rat... |
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Vibrational analysis of substituted benzonitriles. III. Transferability of force constants--the case of some halogeno-, methoxy- and nitro-benzonitriles.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 53A(12) , 2041-8, (1997) A zero-order normal coordinate analysis of both the in-plane and out-of-plane vibrations was made for 2-chloro, 6-fluorobenzonitrile, s-trichlorobenzonitrile, p- and m-methoxybenzonitriles and m-nitrobenzonitrile, transferring the force constants from our ear... |
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Investigation into the regiochemistry of some isoxazoles derived from 1,3-dipolar cycloaddition of 4-nitrobenzonitrile oxide with some dipolarophiles: a combined theoretical and experimental studies.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 79(5) , 1375-80, (2011) Reaction of 4-nitrobenzonitrile oxide (2) which was generated in situ with acrylo nitrile (3), methyl methacrylate (4) and allyl bromide (5) as dipolarphile afforded the new 7a, 8a and 9a compounds respectively. Reactivity and regiochemistry of these reaction... |