2-Cyanobenzaldehyde
2-Cyanobenzaldehyde structure
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Common Name | 2-Cyanobenzaldehyde | ||
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| CAS Number | 7468-67-9 | Molecular Weight | 131.131 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 284.9±23.0 °C at 760 mmHg | |
| Molecular Formula | C8H5NO | Melting Point | 103-105 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 126.1±22.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Diastereoselective one-pot tandem synthesis of 3-substituted isoindolinones: a mechanistic investigation.
J. Org. Chem. 75(17) , 5882-7, (2010) The mechanism of a base-catalyzed one-pot reaction of 2-cyanobenzaldehyde and primary nitroalkanes, to produce 3-substituted isoindolinones, has been investigated. A route starting with a nitroaldol (Henry) reaction, followed by a subsequent cyclization and r... |
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Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones.
Beilstein J. Org. Chem. 11 , 2591-9, (2015) New bifunctional chiral ammonium salts were investigated in an asymmetric cascade synthesis of a key building block for a variety of biologically relevant isoindolinones. With this chiral compound in hand, the development of further transformations allowed fo... |
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The aldol addition of readily enolizable 1, 3-dicarbonyl compounds to 2-cyanobenzaldehyde in the synthesis of novel 3-substituted isoindolinones. More V, et al.
Synthesis 2011(18) , 3027-31, (2011)
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Application of baylis-hillman methodology in a new synthesis of 3-oxo-2, 3-dihydro-1H-isoindoles. Song YS, et al.
J. Heterocycl. Chem. 40(5) , 939-42, (2003)
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Biotransformation of aromatic aldehydes and related compounds by Euglena gracilis Z. Noma Y, et al.
Phytochemistry 30(9) , 2969-72, (1991)
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Novel synthesis of 3-(N-substituted amino)-1-isoindolenones from 2-cyanobenzaldehyde with amines. Sato R, et al.
Chem. Lett. 9 , 1599-1602, (1984)
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