FARNESAL

FARNESAL Structure
FARNESAL structure
Common Name FARNESAL
CAS Number 19317-11-4 Molecular Weight 220.35000
Density 0.868g/cm3 Boiling Point 328.6ºC at 760mmHg
Molecular Formula C15H24O Melting Point N/A
MSDS Chinese USA Flash Point 147.8ºC
Symbol GHS07
GHS07
Signal Word Warning

Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras-E-cadherin pathway.

Cancer Lett. 355(2) , 273-80, (2014)

Aldo-keto reductase 1B10 (AKR1B10) has relatively specific lipid substrates including carbonyls, retinal and farnesal/geranylgeranial. Metabolizing these lipid substrates appears crucial to carcinogenesis, particularly for farnesal/geranylgeranial that involv...

Formation of farnesal and 3-hydroxy-2,3-dihydrofarnesal from farnesol by protoplasts of Botryococcus braunii.

Biochem. Biophys. Res. Commun. 196(3) , 1401-5, (1993)

Farnesal and 3-hydroxy-2,3-dihydrofarnesal (3-hydroxy-3,7,11-trimethyl-6,10-dodecadiene-1-al) were formed from farnesol when the alcohol was incubated with the protoplast of Botryococcus braunii B race strain. This fact suggests the existence of farnesal hydr...

Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal.

J. Org. Chem. 73(7) , 2905-8, (2008)

The sesquiterpene nanaimoal was synthesized in 21% overall yield and in a biomimetic manner. As a key step, the acid-catalyzed cyclization of farnesal under zeolite NaY confinement conditions was used. The intrazeolite cyclization of farnesal affords as major...

Chemical ecology of oribatid mites III. Chemical composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus (Acari: Trhypochthoniidae).

Exp. Appl. Acarol. 29(3-4) , 279-91, (2003)

The composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus, was studied with reference to the related species Trhypochthoniellus crassus. Trhypochthoniellus sp. contained a mixture of seven compounds; (...

Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10

Bioorg. Med. Chem. 18(7) , 2485-90, (2010)

The chromene-3-carboxamide derivatives were found as potent inhibitors of AKR1B10.

Absolute configuration of chiral terpenes in marking pheromones of bumblebees and cuckoo bumblebees.

Chirality 16(4) , 228-33, (2004)

The absolute configurations of citronellol, 2,3-dihydrofarnesol, and 2,3-dihydrofarnesal in male marking pheromones of seven species of bumblebees and cuckoo bumblebees were determined by enantioselective gas chromatography on a capillary column coated with 6...

The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand.

FEBS J. 273(21) , 4983-96, (2006)

The in vivo ligand-binding function and ligand-binding activity of the Drosophila melanogaster retinoid-X receptor (RXR) ortholog, ultraspiracle, toward natural farnesoid products of the ring gland were assessed. Using an equilibrium fluorescence-binding assa...

Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase.

J. Biol. Chem. 276(4) , 2321-4, (2001)

Prenylated proteins contain either a 15-carbon farnesyl or a 20-carbon geranylgeranyl isoprenoid covalently attached via a thioether bond to a cysteine residue at or near their C terminus. As prenylated proteins comprise up to 2% of the total protein in eukar...

Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis.

J. Chem. Ecol. 34(4) , 467-77, (2008)

The southern cowpea weevil, Callosobruchus chinensis (Coleoptera: Bruchidae), is a major pest of stored legumes in warm temperate and tropical climates. The female sex attractant pheromone was extracted from filter-paper shelters taken from containers that ho...

2,3-Dihydrohomofarnesal: female sex attractant pheromone component of Callosobruchus rhodesianus (Pic).

J. Chem. Ecol. 36(8) , 824-33, (2010)

Callosobruchus rhodesianus (Pic) (Coleoptera: Chrysomelidae: Bruchinae) is a pest of stored legumes through the Afro-tropical region. In laboratory bioassays, males of C. rhodesianus were attracted to volatiles collected from virgin females. Collections were ...