Trimethyldiaminophenazathonium Chloride
Trimethyldiaminophenazathonium Chloride structure
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Common Name | Trimethyldiaminophenazathonium Chloride | ||
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| CAS Number | 531-55-5 | Molecular Weight | 305.826 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H16ClN3S | Melting Point | 205-210 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Involvement of Nod2 in the innate immune response elicited by malarial pigment hemozoin.
Microbes Infect. 17(3) , 184-94, (2015) In malaria, the evidence concerning the nucleotide-binding, oligomerization domain (NOD) 2 (NOD2) receptor is fragmented and the stimuli that might activate NOD2 are not well characterized. We investigated the role of NOD2 in vitro in the response of macropha... |
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Azure B and a synthetic structural analogue of methylene blue, ethylthioninium chloride, present with antidepressant-like properties.
Life Sci. 117(2) , 56-66, (2015) The phenothiazinium compound, methylene blue (MB), possesses diverse pharmacological actions and is attracting attention for the treatment of bipolar disorder and Alzheimer's disease. MB acts on both monoamine oxidase (MAO) and the nitric oxide (NO)-cGMP path... |
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Ligand polarizability contributes to tau fibril binding affinity.
Bioorg. Med. Chem. 19 , 5147-54, (2011) Whole brain imaging of tau-bearing neurofibrillary lesions has the potential to improve the premortem diagnosis and staging of Alzheimer's disease. Diverse compounds with high affinity for tau aggregates have been reported from high-throughput screens, but th... |
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How Romanowsky stains work and why they remain valuable - including a proposed universal Romanowsky staining mechanism and a rational troubleshooting scheme.
Biotech. Histochem. 86(1) , 36-51, (2011) An introduction to the nomenclature and concept of "Romanowsky stains" is followed by a brief account of the dyes involved and especially the crucial role of azure B and of the impurity of most commercial dye lots. Technical features of standardized and tradi... |
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Application of a novel alkali-tolerant thermostable DyP-type peroxidase from Saccharomonospora viridis DSM 43017 in biobleaching of eucalyptus kraft pulp.
PLoS ONE 9(10) , e110319, (2014) Saccharomonospora viridis is a thermophilic actinomycete that may have biotechnological applications because of its dye decolorizing activity, though the enzymatic oxidative system responsible for this activity remains elusive. Bioinformatic analysis revealed... |
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H2S induced coma and cardiogenic shock in the rat: Effects of phenothiazinium chromophores.
Clin. Toxicol. (Phila.) 53 , 525-39, (2015) Hydrogen sulfide (H2S) intoxication produces an acute depression in cardiac contractility-induced circulatory failure, which has been shown to be one of the major contributors to the lethality of H2S intoxication or to the neurological sequelae in surviving a... |
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A study of lymphoid organs and serum proinflammatory cytokines in pigs infected with African swine fever virus genotype II.
Arch. Virol. 160 , 1407-14, (2015) African swine fever virus (ASFV), the causative agent of one of the most important viral diseases of domestic pigs for which no vaccine is available, causes immune system disorders in infected animals. In this study, the serum levels of proinflammatory cytoki... |
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Analysis and testing of biological stains--the Biological Stain Commission Procedures.
Biotech. Histochem. 77(5&6) , 237-275, (2002)
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Clinical association with urinary glycosaminoglycans and urolithiasis.
Urology 59(4) , 495-9, (2002) To determine the clinical association between urinary glycosaminoglycan (GAG) concentration and kidney stone disease.Thirty-five patients (14 women and 21 men) with a history of stone disease and 37 controls (13 women and 24 men) were evaluated for urinary GA... |
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Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins.
J. Biol. Chem. 280(9) , 7614-23, (2005) Tau protein is the major component of the intraneuronal filamentous inclusions that constitute defining neuropathological characteristics of Alzheimer's disease and other tauopathies. The discovery of tau gene mutations in familial forms of frontotemporal dem... |