p-Dimethylaminobenzaldehyde

p-Dimethylaminobenzaldehyde Structure
p-Dimethylaminobenzaldehyde structure
Common Name p-Dimethylaminobenzaldehyde
CAS Number 100-10-7 Molecular Weight 149.190
Density 1.1±0.1 g/cm3 Boiling Point 176-177 ºC (17 mmHg)
Molecular Formula C9H11NO Melting Point 72-75 °C(lit.)
MSDS USA Flash Point 164 ºC
Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger

In vitro characterization of self-assembled anterior cruciate ligament cell spheroids for ligament tissue engineering.

Histochem. Cell Biol. 143(3) , 289-300, (2015)

Tissue engineering of an anterior cruciate ligament (ACL) implant with functional enthesis requires site-directed seeding of different cell types on the same scaffold. Therefore, we studied the suitability of self-assembled three-dimensional spheroids generat...

Modulating notochordal differentiation of human induced pluripotent stem cells using natural nucleus pulposus tissue matrix.

PLoS ONE 9(7) , e100885, (2014)

Human induced pluripotent stem cells (hiPSCs) can differentiate into notochordal cell (NC)-like cells when cultured in the presence of natural porcine nucleus pulposus (NP) tissue matrix. The method promises massive production of high-quality, functional cell...

Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.

Am. J. Pathol. 185 , 2923-38, (2015)

Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Lung macrophages have been reported to regulate both progression and remission of bleomycin-induced diffuse PF. However, it remains unclear how macrophages contribute to silica-induced ...

Inhibitory effects of the ethyl acetate extract from bulbs of Scilla scilloides on lipoxygenase and hyaluronidase activities.

Pharm. Biol. 52(10) , 1351-7, (2014)

Scilla scilloides Druce (Liliaceae) is a folk medicine to treat dermal inflammation; however, the medicinal properties of this plant have not been completely established.The current study investigates the potent anti-inflammatory effects of S. scilloides bulb...

Controlling osteogenic stem cell differentiation via soft bioinspired hydrogels.

PLoS ONE 9(6) , e98640, (2014)

Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is guided by various physical and biochemical factors. Among these factors, modulus (i.e., rigidiy) of the ECM has gained significant attention as a physical osteoinductive signal that can con...

Human renal tubular epithelial cells suppress alloreactive T cell proliferation.

Clin. Exp. Immunol. 179(3) , 509-19, (2015)

Renal tubular epithelial cells (TECs) are one of the main targets of alloreactive T cells during acute rejection. We hypothesize that TECs modulate the outcome of alloimmunity by executing immunosuppressive effects in order to dampen the local inflammation. W...

Collagen content does not alter the passive mechanical properties of fibrotic skeletal muscle in mdx mice.

Am. J. Physiol. Cell Physiol. 306(10) , C889-98, (2014)

Many skeletal muscle diseases are associated with progressive fibrosis leading to impaired muscle function. Collagen within the extracellular matrix is the primary structural protein providing a mechanical scaffold for cells within tissues. During fibrosis co...

Seed oil of Joannesia princeps improves cutaneous wound closure in experimental mice.

Acta Histochem. 116(7) , 1169-77, (2014)

Joannesia princeps (Cotieira) is a well known medicinal plant in Brazil, however, the therapeutic effects of oil obtained from its seeds have still not been demonstrated. The beneficial effects of J. princeps seed oil on cutaneous wound healing on the back of...

Targeting delivery of etoposide to inhibit the growth of human glioblastoma multiforme using lactoferrin- and folic acid-grafted poly(lactide-co-glycolide) nanoparticles.

Int. J. Pharm. 479(1) , 138-49, (2015)

Lactoferrin (Lf) and folic acid (FA) were crosslinked on poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) for transporting etoposide across the blood-brain barrier (BBB) and treating human brain malignant glioblastoma. Lf- and FA-grafted PLGA NPs (Lf/FA/...

Induction of indoleamine 2,3-dioxygenase by Borrelia burgdorferi in human immune cells correlates with pathogenic potential.

J. Leukoc. Biol. 97(2) , 379-90, (2015)

Borrelia burgdorferi, the bacterial agent of Lyme disease, induces the production of type I IFNs by human DCs through TLR7 and TLR9 signaling. This type I IFN response occurs in a genotype-dependent manner, with significantly higher levels of IFN-α elicited b...