Salicylic acid
Salicylic acid structure
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Common Name | Salicylic acid | ||
|---|---|---|---|---|
| CAS Number | 69-72-7 | Molecular Weight | 138.121 | |
| Density | 1.44 | Boiling Point | 211 ºC (20 mmHg) | |
| Molecular Formula | C7H6O3 | Melting Point | 158-161 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 157 ºC | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Inhibition of aberrant complement activation by a dimer of acetylsalicylic acid.
Neurobiol. Aging 36 , 2748-56, (2015) We here report synthesis for the first time of the acetyl salicylic acid dimer 5,5'-methylenebis(2-acetoxybenzoic acid) (DAS). DAS inhibits aberrant complement activation by selectively blocking factor D of the alternative complement pathway and C9 of the mem... |
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Graphene modified glassy carbon sensor for the determination of aspirin metabolites in human biological samples.
Talanta 143 , 328-34, (2015) A graphene modified glassy carbon (GR/GCE) sensor has been developed for the determination of aspirin metabolites 2,3- and 2,5-dihydroxybenzoic acids (2,3- and 2,5-DHB). The modified sensor was characterized by Field Emission Scanning Electron Microscopy and ... |
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Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.
AAPS J. 17(1) , 256-67, (2015) Carbohydrate functionalization of nanoparticles allows for targeting of C-type lectin receptors. This family of pattern recognition receptors expressed on innate immune cells, such as macrophages and dendritic cells, can be used to modulate immune responses. ... |
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Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity.
Int. J. Nanomedicine 10 , 229-43, (2015) H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhyd... |
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Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.
PLoS Negl. Trop. Dis. 9 , e0004173, (2015) Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. ... |
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Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action.
J. Thromb. Haemost. 12(8) , 1320-30, (2014) Even though the acetylation of platelet cyclooxygenase (COX)-1 at serine-529 is the direct mechanism of action of low-dose aspirin, its antiplatelet effect has been characterized using indirect indexes of COX-1 activity.We performed a clinical study with ente... |
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Pathway as a pharmacological target for herbal medicines: an investigation from reduning injection.
PLoS ONE 10(4) , e0123109, (2015) As a rich natural resource for drug discovery, Traditional Chinese Medicine (TCM) plays an important role in complementary and alternative medical systems. TCM shows a daunting complexity of compounds featuring multi-components and multi-targets to cure disea... |
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Binding and Anticancer Properties of Plumbagin with Human Serum Albumin.
Chem. Biol. Drug Des. 86 , 362-9, (2015) Plumbagin has received extensive attention as a promising anticancer drug. Therefore, we investigated the binding and anticancer properties of plumbagin with human serum albumin. Fluorescence results demonstrated that plumbagin interacts with human serum albu... |
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Molecularly imprinted polymers with synthetic dummy template for simultaneously selective removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts.
J. Chromatogr. A. 1368 , 44-51, (2014) Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy template molecule with similar structural skeleton to GAs, 6-... |
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Inhibitory Effect of Dried Pomegranate Concentration Powder on Melanogenesis in B16F10 Melanoma Cells; Involvement of p38 and PKA Signaling Pathways.
Int. J. Mol. Sci. 16 , 24219-42, (2015) Plants rich in antioxidant substances may be useful for preventing skin aging. Pomegranates, containing flavonoids and other polyphenolic compounds, are widely consumed due to their beneficial properties. We examined the underlying mechanisms of dried pomegra... |