N-Benzyl-2-bromo-N-phenylbutanamide

N-Benzyl-2-bromo-N-phenylbutanamide Structure
N-Benzyl-2-bromo-N-phenylbutanamide structure
Common Name N-Benzyl-2-bromo-N-phenylbutanamide
CAS Number 851073-30-8 Molecular Weight 332.23500
Density N/A Boiling Point N/A
Molecular Formula C17H18BrNO Melting Point N/A
MSDS Chinese USA Flash Point >230 °F
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Asymmetric nickel-catalyzed Negishi cross-couplings of secondary alpha-bromo amides with organozinc reagents.

J. Am. Chem. Soc. 127 , 4594, (2005)

A Ni/Pybox catalyst achieves the asymmetric cross-coupling of secondary alpha-bromo amides with organozinc reagents. The process tolerates a variety of functional groups and affords the desired product in good yield and in high enantiomeric excess.