STRYCHNINE
STRYCHNINE structure
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Common Name | STRYCHNINE | ||
|---|---|---|---|---|
| CAS Number | 60-41-3 | Molecular Weight | 766.90200 | |
| Density | N/A | Boiling Point | 559.9ºC at 760 mmHg | |
| Molecular Formula | C42H46N4O8S | Melting Point | 284-286 °C(lit.) | |
| MSDS | USA | Flash Point | 292.4ºC | |
| Symbol |
GHS06, GHS09 |
Signal Word | Danger | |
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Subregion-Specific Modulation of Excitatory Input and Dopaminergic Output in the Striatum by Tonically Activated Glycine and GABA(A) Receptors.
Front. Syst. Neurosci. 5 , 85, (2011) The flow of cortical information through the basal ganglia is a complex spatiotemporal pattern of increased and decreased firing. The striatum is the biggest input nucleus to the basal ganglia and the aim of this study was to assess the role of inhibitory GAB... |
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Role of glycine receptors in glycine-induced LTD in hippocampal CA1 pyramidal neurons.
Neuropsychopharmacology 36 , 1948-1958, (2011) Glycine in the hippocampus can exert its effect on both synaptic NMDA receptors (NMDARs) and extrasynaptic functional glycine receptors (GlyRs) via distinct binding sites. Previous studies have reported that glycine induces long-term potentiation (LTP) throug... |
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The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors.
Addict. Biol. 16 , 591-599, (2011) Studies have indicated that the metabotropic glutamate receptor 5 (mGluR5) antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) decreases ethanol self-administration, and the same receptor type was also suggested to be involved in the mechanism of action of ... |
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Orexin neurons receive glycinergic innervations.
PLoS ONE 6 , e25076, (2011) Glycine, a nonessential amino-acid that acts as an inhibitory neurotransmitter in the central nervous system, is currently used as a dietary supplement to improve the quality of sleep, but its mechanism of action is poorly understood. We confirmed the effects... |