Polymyxin B Sulfate
Polymyxin B Sulfate structure
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Common Name | Polymyxin B Sulfate | ||
|---|---|---|---|---|
| CAS Number | 1405-20-5 | Molecular Weight | 1287.53 (PolymyxinB2Sulfate) | |
| Density | N/A | Boiling Point | 1651ºC at 760 mmHg | |
| Molecular Formula | C55H96N16O13.H2SO4(PolymyxinB2Sulfate) | Melting Point | 217-220°C (dec.) | |
| MSDS | Chinese USA | Flash Point | 952.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Bacterial lipopolysaccharide induces rainbow trout myotube atrophy via Akt/FoxO1/Atrogin-1 signaling pathway.
Acta Biochim. Biophys. Sin. (Shanghai) 47 , 932-7, (2015) Lipopolysaccharide (LPS) is considered as a powerful inducer of muscle atrophy in higher vertebrates due to skeletal muscle cell recognition of the endotoxin and a consequent activation of catabolic signaling pathways. In contrast, there is no evidence of LPS... |
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The interaction of polysaccharide from Auricularia polytricha with quantum dots and the protection of plasmid DNA from damage.
Appl. Biochem. Biotechnol. 169(8) , 2263-72, (2013) As a kind of folk medicine, edible mushrooms are known to be of medicinal characteristics, for example antitumor activity. However, the mechanism is not clear. In this study, the fluorescence (FL) spectroscopy was used to study the binding reactions of polysa... |
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A critical role for CD8 T cells in a nonhuman primate model of tuberculosis.
PLoS Pathog. 5 , e1000392, (2009) The role of CD8 T cells in anti-tuberculosis immunity in humans remains unknown, and studies of CD8 T cell-mediated protection against tuberculosis in mice have yielded controversial results. Unlike mice, humans and nonhuman primates share a number of importa... |
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Streptococcus pyogenes polymyxin B-resistant mutants display enhanced ExPortal integrity.
J. Bacteriol. 196(14) , 2563-77, (2014) The ExPortal protein secretion organelle in Streptococcus pyogenes is an anionic phospholipid-containing membrane microdomain enriched in Sec translocons and postsecretion protein biogenesis factors. Polymyxin B binds to and disrupts ExPortal integrity, resul... |
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Clearance of nasal Staphylococcus aureus colonization with triple antibiotic ointment.
Journal. of. Drugs in. Dermatology. 11(12) , 1490-2, (2012) The prevalence of Staphylococcus aureus colonization of healthcare workers is reported at 30%, with colonization rates for methicillin-resistant S aureus (MRSA) reported between 2.0% and 8.5% among industrialized nations. The anterior nares are the most frequ... |
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Direct hemoperfusion with a polymyxin B column versus vasopressin for gram negative septic shock: a matched cohort study of the effect on survival.
Clin. Nephrol. 79(6) , 463-70, (2013) Vasopressin and direct hemoperfusion with an immobilized polymyxin B column (PMX) have emerged recently as treatments for septic shock. This study assessed the impact of these two treatments on the survival of patients with septic shock.A retrospective, match... |
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Polymyxin B hemoperfusion: matching the cure to the disease.
Crit. Care Med. 42(5) , 1309-10, (2014)
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The novel polymyxin derivative NAB739 is remarkably less cytotoxic than polymyxin B and colistin to human kidney proximal tubular cells.
Int. J. Antimicrob. Agents 41(3) , 292-3, (2013)
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Development of a selective enrichment broth supplemented with bacteriological charcoal and a high concentration of polymyxin B for the detection of Campylobacter jejuni and Campylobacter coli in chicken carcass rinses.
Int. J. Food Microbiol. 162(3) , 308-10, (2013) A new Campylobacter-selective enrichment broth supplemented with bacteriological charcoal and a high concentration of polymyxin B was developed (charcoal-cefoperazone-polymyxin B-deoxycholate broth; CCPD broth). We compared the ability of CCPD broth to detect... |
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Successful treatment of severe amiodarone pulmonary toxicity with polymyxin B-immobilized fiber column direct hemoperfusion.
Chest 143(4) , 1146-50, (2013) Amiodarone pulmonary toxicity (APT) is the most serious side effect of amiodarone. Although severe APT, such as ARDS, is rare, mortality of severe APT is high. Polymyxin B-immobilized fiber column direct hemoperfusion (PMX-DHP) is a medical device that reduce... |